Basic principles Flashcards

1
Q

Passive movement of non protein bound drugs bet blood and extravascular space; affected by drug concentrate and charge

A

Aqueous diffusion

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2
Q

What law is related to aqueous diffusion?

A

Fick’s law of Diffusion

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3
Q

Most important limiting factor for permeation?

A

Lipid Diffusion

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4
Q

Weak acids and weak bases is diffused through?

A

Lipid Diffusion

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5
Q

2 pharmacologic implications in Fick’s Law of Diffusion

A

Absorption is faster in organs with 1) larger SA and 2) thinner membranes

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