Basic Players of the Immune System

Question 1

germ-line encoded pathogen receptors

Answer 1

innate immunity

Question 2

humoral and cell-mediated responses

Answer 2

adaptive immunity

Question 3

What is the response time of the innate immune system?

Answer 3

minutes to hours

Question 4

What is the response time of the adaptive immune system?

Answer 4

5 to 6 days or more

Question 5

Which lymphocytes are associated with humoral immunity?

Answer 5

B lymphocytes

Question 6

Which lymphocytes are associated with cell mediated immunity?

Answer 6

T lymphocytes

Question 7

Name 4 ways antibodies work.

Answer 7

1. Neutralize toxins
2. Agglutinate bacteria
3. Target pathogens for destruction
4. Provide passive immunization

Question 8

Which regions of Abs have only limited variation?

Answer 8

constant regions

Question 9

Antibody structure consists of:

Answer 9

2 identical heavy chains
2 identical light chains
Intra- /inter-chain disulfide covalent bonds

Question 10

Fc region of antibodies determine the ___________________ of Ab.

Answer 10

isotype or class

Question 11

Name the 5 classes of secreted Abs.

Answer 11

IgA
IgD
IgE
IgG
IgM

Question 12

Which classes of Ab have J-chains?

Answer 12

IgA and IgM

Question 13

Which class of Ab has the highest avidity?

Answer 13

IgM

Question 14

Name 4 types of cells developed from common myeloid progenitors.

Answer 14

1. RBC
2. monocytes
3. granulocytes
4. megakaryocytes

Question 15

Name the 4 granulocytes.

Answer 15

1. neutrophils
2. basophils
3. eosinophils
4. mast cells

Question 16

Which cells are derived from lymphoid progenitors? (3)

Answer 16

1. B cells
2. T cells
   (lymphocytes)
3. NK cells

Question 17

Cell considered the first responders to infection.

Answer 17

neutrophils

Question 18

Granules stain with bright pink.

Answer 18

eosinophils

Question 19

Granules stain with blue.

Answer 19

basophils

Question 20

Contains both basic and acidic granules.

Answer 20

neutrophils

Question 21

Are less than 1% of WBCs and are nonphagocytic, with histamine containing granules.

Answer 21

mast cells

Question 22

Which type of myeloid lineage cell forms platelets?

Answer 22

megakaryocytes

Question 23

For which cell is the Ag receptor an antibody?

Answer 23

B cells

Question 24

Clonal selection takes place during the development of which kind of cells?

Answer 24

B and T cells