Basic Pharmacology Flashcards

1
Q

Definition of pharmacology

A

Study of drugs, medicine and pharmaceuticals

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2
Q

What is ‘Clinical Pharmacology and Therapeutics’ (CPT)

A

Teaches the mechanisms and effects of drugs that doctors prescribe to their patient

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3
Q

What is a drug?

A

Active substance with a direct effect in the diagnosis, cure, mitigation, treatment and prevention of disease

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4
Q

What is a placebo?

A

An inactive substance that is administered as though it is a drug, but which has no therapeutic effect

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5
Q

How did pharmacology emerge?

A

Through identifying, purifying and modifying plant-derived molecules

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6
Q

Why are herbal remedies mostly useless?

A
  • Dirty mixtures of multiple ingredients
  • Contaminants may be toxic
  • Active ingredient is often present in unknown amounts
  • No consistent dose to ensure safety
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7
Q

What do ethical pharmaceuticals involve?

A
  • Purification of active molecules to remove contaminants
  • Testing activity of known amounts in biological models
  • Modification of structure to improve activity
  • Testing efficacy, safety, and bioavailability in randomised placebo-controlled clinical trials
  • Stringent legal requirements to prove efficacy and safety
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