Basic Pain Management Flashcards
Mechanism of Pain
Periphery
-Tissue injury, release of chemicals, stimulation of pain receptors, pain travels in C nerve to spinal cord
Spinal cord
-Dorsal horn is first relay station, C nerve connects with second order nerve, travels up the opposite side
Brain
-Thalamus is second relay, connects to cortex, limbic and brainstem
Modulation
-Descending pathway from brain to dorsal horn, inhibits pain signals form periphery
Reverse WHO ladder?
Start at top work down
Local Anaesthetic MOA?
Works on internal membrane in axon to prevent depolarisation
Types of Local Anaesthetics
Esters
-Procaine, amethocaine, cocaine, tetracaine
Amides
-Ropivacaine, levobupivicaine, mepicaine
EMLA(lignocaine:prilocaine) and Ametop(tetracaine 4%)
Local Anaesthetics Max Dose
Lignocaine 3mg/kg, 7 with adrenalin
Bupivicaine/Levopbupivicaine 2,2
Prilocaine 6,9
Convert 0.25% Lignocaine
Multiply by ten to get dose in 1ml (2.5mg/ml in this case)
Symptoms of Local Anaesthesia Toxicity
Tingling sensation around mouth, ringing in ears, tonic-clonic seizure
Where does spinal cord end in adults?
L1
Where does subarachnoid space end?
S1
Where can you do a spinal and epidural block?
Spinal -L4/5, L3/4, L2/3 Epidural -In theory, anywhere -Risk of cord damage if done above L1, usually
Where does epidural space end?
Sacrococcygeal hiatus
Epidural Needle Structures
Skin, subcutaneous fat, supraspinous ligament, interspinous ligament, ligament flavum