Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

USMLE Step 1 PREP BASIC IMMUNOLOGY AND BIOCHEM > Basic Immunology > Flashcards

Basic Immunology Flashcards

1
Q

How many proteins make a histone?

A

8

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What amino acids make up histones?

A

Lysine and arginine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What does a nucleosome comprise of?

A

Histone, condensed DNA wrapped twice around histone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is chromatin comprised of?

A

Nucleosomes and linker DNA like beads on a string

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Name 2 essential amino acids

A

Lysine and leucine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What occurs during S phase of mitosis?

A

Genomic material and histones are made

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How does mitochondria DNA differ from other DNA?

A

Mitochondria have their own DNA, the DNA is circular, do not use histones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the primary organs of the immune system? (Primary lymphoid organs)

A

Bone Marrow
Thymus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the secondary organs of the immune system? (Secondary lymphoid organ)

A

Spleen
Lymph nodes
Tonsils
Peyer’s patches

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the function of the bone marrow?

A

Creation of immune cells
(Lymphocytes, macrophages, neutrophils)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the parts of the lymph node

A

Capsule with trabeculae
Cortex that contains follicles
Paracortex
Medulla (medullary sinus and cords)
Efferents
Afferents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the function of the thymus?

A

Maturation of T cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the functions of the lymph nodes?

A

Activate immune response
Circulation of B and T cells
Filtration by macrophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What cells are found in the cortex?

A

B lymphocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is found in the paracortex?

A

venules and T lymphocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What cells are found in the medullary sinus?

A

Macrophages and reticular cells

17
Q

What cells are found in the medullary cords?

A

Closely packed Lymphocytes and plasma cells

18
Q

What can happen to paracortex when certain infection and viral illnesses occur?

A

Hyperplasia aka clinically- lymphadenopathy

19
Q

Differences between primary and secondary follicles

A

Primary - dense, quiescent
Secondary - pale germinal centers and active

20
Q

What do the medullary sinuses connect with?

A

Efferent lymphatics

21
Q

Role of venules in paracortex

A

T and B lymphocytes enter lymph nodes from blood through these

USMLE Step 1 PREP BASIC IMMUNOLOGY AND BIOCHEM (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions