BASIC IMMUNOLOGY Flashcards
it refers to the ability of the host to fight diseases through body defenses.
IMMUNITY
the study of immune response?
IMMUNOLOGY
the lack of immunity is knows an?
SUSCEPTIBILITY
Two types of immunity:
INNATE
ADAPTIVE
type of immunity that is present as birth
INNATE
type of immunity that is acquired and acts when microbes overcame the innate defenses
ADAPTIVE
general type of immunity
INNATE
specific type of immunity
ADAPTIVE
NORMAL MICROBIOTA, NORMAL FLORA OR INDIGENOUS FLORA
this consists of microorganisms that inhabit the human body but normally do not cause disease.
NORMAL MICROBIOTA, NORMAL FLORA OR INDIGENOUS FLORA
TWO TYPES OF NORMAL MICROBIOTA:
TRANSIENT MICROBIOTA
RESIDENT MICROBIOTA
those microbes that inhabit the body for weeks or months but later disappear?
TRANSIENT MICROBIOTA
microbes that are fixed and regularly found on a specific site of the body?
RESIDENT MICROBIOTA
ROLES OF NORMAL MICROBIOTA:
• Inhibit the growth of pathogenic microbes
• Protects the body from invasive
microbes
• Synthesize vitamins important to
humans
• Aid in digestion and metabolism
The relationship between the normal microbiota and the host is called
SYMBIOSIS
One organism benefits, and the other is unaffected?
COMMENSALISM
both organisms benefit?
MUTUALISM
One organisms benefit at the expense of the other?
PARASITISM
E.coli gives us?
VITAMIN K
The site or part of the body that inhabit most of the normal microbiota?
COLON
the first line of defense against environmental disease- causing microbes are the _______?
SKIN AND MUCOUS MEMBRANES
are the barriers that prevent the entry or cause the removal of microbes from the surface of the body?
PHYSICAL FACTORS
are the substances produced by the body to inhibit or completely destroy microbial growth?
CHEMICAL FACTORS
Provide tears that wash away microbes
LACRIMAL APPARATUS
Dilutes and washes microbes from mouth
SALIVA
Filter and trap microbes and dust in nose
HAIRS
It traps and removes microbes from upper respiratory tract
CILIA
Prevents microbes from entering lower respiratory tract
EPIGLOTTIS
Prevents microbes from entering ear
EARWAX
Washes microbes from urethra to prevent colonization in genitourinary tract
URINE
Moves microbes out of the body?
VAGINAL SECRETIONS
Expel microbes from body
PERISTALSIS, DEFECATION, VOMITING, AND DIARRHEA
Traps mucus in respiratory and gastrointestinal tracts?
MUCUS
Intact skin forms a physical barrier to the entrance of microbes; shedding helps removes microbes?
EPIDERMIS OF SKIN
Inhibit the entrance of many microbes, but not as effectively as intact skin.
MUCOUS MEMBRANES
Two types of white blood cells:
AGRANULOCYTE
GRANULOCYTE
white blood cell that has no granules?
AGRANULOCYTE
White blood cell that has granules?
GRANULOCYTE
Differentiate into macrophages and dendritic cells in response to inflammation.
MONOCYTE
Differentiates into macrophages and dendritic cells in response to inflammation.
MONOCYTE
Differentiates into macrophages and dendritic cells in response to inflammation.
MONOCYTE
First responders at the site of infection or trauma, this abundant phagocytic cell represents 50-60 percent of all leukocytes. Releases toxins that kills or inhibit bacteria and fungi and recruits other immune cells to the site of infection.
NEUTROPHIL
Responsible for defense against parasites.
Releases histamines that cause inflammation and may be responsible for allergic reactions.
BASOPHIL
Releases toxins that kill bacteria and parasites but also causes tissue damage.
EOSINOPHIL
Dilates blood vessels and induces inflammation through release of histamines and heparin. Recruits macrophages and neutrophils. Involved in wound healing and defense against pathogens but can also be responsible for allergic reactions.
MAST CELL
Phagocytic cell that consumes foreign pathogens and cancer cells. Stimulates response of other immune cells.
MACROPHAGE
Kills tumor cells and virus-infected cells.
NATURAL KILLER CELL
Presents antigens on its surface, thereby triggering adaptive immunity.
DENDRITIC CELL
It is very important in inflammation?
HISTAMINE
Immune system cells communicate with each other through?
CYTOKINES
It is a signaling molecules, and it act as cellular mediators/messenger?
CYTOKINES
Some cell secretes and receives cytokine signal
AUTOCRINE
Cytokine signal secreted to a nearby cell.
PARACRINE
Cytokine signal secreted to circulatory system, travels to distant cells.
ENDORCRINE
Antiviral proteins
INTERFERON FAMILY
Direct cell migration, adhesion and activation.
CHEMOKINE FAMILY
Regulate inflammatory and immune response
TUMOUR NECROSIS FACTOR FAMILY
Variety of actions dependent upon interleukin and cell type
INTERLEUKIN FAMILY
Promote cell proliferation and differentiation
HAEMATOPOIETINS
Regulation of immune cells
TRANSFORMING GROWTH FACTOR BETA FAMILY
too much cytokine is called?
CYTOKINE STORM