Basic - General Anesthesia Flashcards
Read the 11 non-reassuring findings from ASA as predictors of difficult airway
- Long incisors
- Prominent overbite
- Cannot bring mandibular incisors anterior to maxillary incisors
- < 3cm inter-incisor distance
- Uvula not visible when tongue protruded
- High arched or narrow palate
- Mandibular space stiff or occupied by mass
- < 3 ordinary finger breadth TM distance
- Short neck length
- Thick neck
- Decreased extension or flexion of neck
*Decaying teeth is NOT a predictor
The liver receives ___% of total cardiac output
30%
- 3/4 by portal vein
- 1/4 by hepatic artery
_____ cells and specialized pathways detoxify substances, rendering them into harmless compounds. This process is the primary reason why ______ metabolism is effective.
Kupffer cells
First-pass
Liver synthesizes all of the procoagulants EXCEPT ____
Factors III, IV, and VIII
*overlaps with vit K dependent proteins 1972, giving vit K will differentiate if it is a deficiency in Vit K or hepatic procoagulants
Factor VIII is produced in ____
endothelial cells and bone marrow
Vit K dependent proteins are ______
Factors II, VII, IX, X
1972
*giving vit K will differentiate if pts with prolonged PT has a deficiency in Vit K or hepatic procoagulants
(ALT/AST) is the main cytoplasmic liver enzyme
ALT
*AST can be found in other body tissues
What can low albumin indicate?
- Chronic liver injury
- Renal loss
- Inc albumin catabolism
- Expansion plasma volume
- Maldistribution
Laryngospasm is a reflex response that involves the ADDuction of the ______, with motor innervation by the recurrent laryngeal n.
true and false vocal cords.
Individual risk factors of post op cognitive dysfunction
- Adv age
- Lower education level
- H.o Previous CVA with NO residual impairment
*Independent of type of surgery. ie. NOT cardiac sx
Anyone with a MI without intervention should wait ____ days before elective sx
60 days
Emergent vs Urgent surgery
Emergent: Life or limb is threatened if not in OR w/in 6 hours
Urgent surgery: Life or limb if not w/in 24 hrs
After an MI, Pts should wait ___ days after balloon angioplasty before elective surgery
14 days
2 antidotes for extravasation
- Hyaluronidase
- pediatric, TPN - Phentolamine
- alpha blocker -> vasodilates
How to administer phentolamine if phenylephrine extravasated?
Dilute 5 mg of phentolamine to 0.5mg/mL, then inject 1 mL increments into area surrounding extravasation site
Elevate limb
After fentanyl, which med is the most commonly abused opioid amongst anesthesiologist?
Sufentanil > Meperidine > Morphine > oral drugs
Inhaled anesthetic induction techniques are (improved/worsened) by benzos and (improved/worsened) by opioid
improved
worsened
Stage II excitation is (increased/decreased) with masked induction with sevoflurane
decreased
ASA 4 vs 5?
4: severe systemic disease, constant threat to life
- Recent < 3 mo TIA or MI
- ESRD NOT on regular dialysis
5: Moribund pt not expected to survive w/o operation
- Massive trauma
- ICH w/ mass effect
Severe aortic stenosis:
Valve area:
Transvalvular pressure gradient:
Valve area: < 0.8 cm^2
Transvalvular pressure gradient: > 50 mmHg
Where do you want to keep HR in pts with AR?
> 80bpm to decrease diastolic time and decrease time for regurgitation
Factor VII has a the shortest half life of the vit K dep factors, it has a half life of __, and can serve as an early measure of hepatic dysfunction by measuring ____
6 hours
PT/INR
Platelets are produced in the _____, and can be sequestered in the ____ secondary to portal hypertension
bone marrow
spleen
Factor VIII is produced by _______ (4). It is generally bound to vWF in blood.
- Vascular endothelium
- Renal tubular and glomerular cells
- Megakaryocytes
- Hepatic sinusoidal cells