Basic Exam Flashcards
drugs to avoid in porphyria
etomidate, phenytoin, ergots, sulfa, barbituates
presentation of propofol infusion syndrome
hyperkalemia, arrhythmias, metabolic acidosis, hepatomegaly
egg allergy and propofol
most people allergic to egg white. Propofol made with egg yolk proteins. Clinically..do not give to pts with anaphylactic egg allergies
tx of etomidate associated myoclonus
opoids or benzos
etomidate inhibits which adrenal enzyme
11Beta-hydroxylase
sedative that causes increased seizure duration
etomidate
why does 1-chloroprocaine have quick onset?
given in high concentration. Has high pkA (9) so you would expect it to have slow onset
local anesthetics site of systemic absorption (most absorption to least absorption)
Bicepss “ Blood, intercostal, caudal, epidural, plexus (brachial), sciatic, subcutaneous”
total % of brain oxygen consumption
20%
normal ICP
5-15 mmHg
normal cerebral blood flow
50ml/100g/min
CPP (cerebral perfusion) equation
CPP=MAP- (ICP or CVP which ever is higher)
cerebral blood flow changes ___% for every 1 degree change in temperature
5-7%
cerebral blood flow changes ___ for every 1mmHg change in PaCO2
2%
anesthetics that increase amplitude in sensory evoked potentials
- ketamine
2. etomidate
accessory muscles of inspiration
intercostals, cervical strap muscles
how soon after burns/crush injury can hyperkalemia occur with succ?
24 hours
conus medullarus in adults ends at ____
dural sac in adults ends at_____
S1-S2, L1/2
infants- S3, L3
Bohr effect
bOhr—oxygen offloading. Hgb releases O2 in areas of high CO2
nerve that innervates cricothyroid muscle
external branch of superior laryngeal (adducts vocal cords)
nerve that innervates all intrinsic muscle of larynx except cricothyroid
recurrent laryngeal
chronic phenytoin use _____ duration of non-depolarizing blocker
decreases
only acetycholinesterase inhibitor that crosses BBB
physostigmine (tertiary amine)
order of rebreathing in mapleston circuits in spontaneous ventilation (most to least)
A >D > C > B “All dogs can breath” (spontaneously)
spontAneous (A Most effecient)
