Basic Electrophysical Properties

Question 1

Basic Model of TRUE Equilibrium Potential

Answer 1

Question 2

Relationship between Extracellular K+ concentration and transmembrane potential

Answer 2

Question 3

Ohm’s Law

Answer 3

E=IR

Question 4

Typical Cellular Potentials

Answer 4

Question 5

Electrodiffusion Model of Cell Membrane

Answer 5

Question 6

Requirements for an Ion to Contribute to Transmembrane Potential (a Polyionic Transmembrane Diffusion Potential)

Answer 6

Equilibrium potential for that ion IS NOT equal to the transmembrane potential.

Ion crosses cell membrane through a GATED channel.

Ion has to be ACTIVELY TRANSPORTED to maintain its electrochemical gradient, i.e. the equilibrium potential for that ion.

Question 7

GHK Equation for Monovalent Ions

Answer 7

Equilibrium potential for that ion IS NOT equal to the transmembrane potential.

Ion crosses cell membrane through a GATED channel.

Ion has to be ACTIVELY TRANSPORTED to maintain its electrochemical gradient, i.e. the equilibrium potential for that ion.

Question 8

Transmembrane Potential during rest and action potential

Answer 8

Rest: -75mV

Action Potential: +65mV