Basic ADRs by Class Flashcards
Cholinergic ADRs
increased SLUD
decreased HR
increased sweating
Anticholinergic ADRs
decreased SLUD
increased HR
decreased sweating
increased risk of falls in elderly (amnesia/orthostasis)
A1 Agonist ADRs
raises BP
A2 Agonist ADRs
falls in elderly
major issue if non-compliant, such as co-administration of BBs, polypharmacy, lack of understanding of disease
A1 Antagonist ADRs
orthostasis
increases risk of death when used for BP as first line agent
reflex tachycardia
B1 Agonist ADRs
arrythmias
increased HR
increased risk of death when used in outpatient and end stage HF
B2 Agonist ADRs
possible systemic absorption
increases HR/palpitations
Mixed A1/B1 Agonist ADRs
orally:
wt loss
growth suppression in children
possible increase in HR/BP
IV:
arrythmias
excessive vasoconstriction at capillary sites
B Antagonist ADRs
excessive decrease in HR/BP
depression
orthostasis
bronchoconstriction
Thiazide ADRs
Hypotension
dizziness
headache
hypokalemia
beta blocker ADRs
bronchoconstriction
bradycardia
masks symptoms of hypoglycemia
fatigue
depression
ace/arb ADRs
hypotension
hyperkalemia
dry cough - ACE
angioedema - this is an allergy,, bad!!
acute kidney injury
dihydropyridine CCB ADRs
hypotension
dizziness
headache
peripheral edema
non-dihydropyridine CCB ADRs
hypotension
bradycardia
headache
fatigue
dizziness
Nitrates ADRs
headache
reflex tachycardia
dizziness
orthostatic hypotension
