basal ganglia part 1 Flashcards

1
Q
A
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2
Q

The basal ganglia (basal nuclei) are a group of —– ——nuclei.

A

The basal ganglia (basal nuclei) are a group of functionally related nuclei.

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3
Q

Subthalamic Nucleus (STN)

A

located in diencephalon

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5
Q

Dopaminergic neurons

A

are located in dorsal part of the substantia nigra

(cmpact part

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6
Q

also located medially in ventral tegmental area.

A

Dopaminergic neurons

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7
Q

Substantia Nigra (SN)

Compact Part (SNc) and Reticular Part (SNr)

A

in midbrain

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8
Q
A
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10
Q
A
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12
Q
A
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13
Q

dopamine

A

“reward system

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14
Q

The substantia nigra (reticular part) functions with the

—–as the output from the —-.

A

The substantia nigra (reticular part) functions with the GPi as the output from the BG.

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16
Q

ventral region of continuity btwn caudate and putamen

A

striatum

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18
Q

lenticular nucleus

A

putamen

gpe

gpi

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21
Q

cognition processes and control of movements.

A

dopamine

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22
Q

dopamine

A

enjoyment and pleasure, which reinforces and motivates

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23
Q

extrapyramidal system”

A

describes the nuclei and pathways of the BG

termed in 1900 by early 1900s Kinnier Wilson

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24
Q

influences motor and non motor sysem

A

basal ganglia

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25
Q

A lesion to —- —— of the BG will disrupt movement

A

A lesion to one or more of the BG will disrupt movement

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26
Q

Absence of spontaneous movement/ slowness of movement

Inability to inhibit unwanted movements

A

A lesion to one or more of the BG

27
Q

TF BG directly innervate LMNs in the spinal cord or cranial nerve nuclei;

A

F BG do NOT directly innervate LMNs in the spinal cord or cranial nerve nuclei;

28
Q

TF lesion to one or more of the BG produce paralysis

A

lesion to one or more of the BG does not produce paralysis

29
Q

tf BG only influence motor actions

A

t BG only influence motor actions

30
Q

Hypokinetic Disorder

A

Parkinson’s Disease

31
Q

loss of dopaminergic neurons in the SNc

A

Parkinson’s Disease a hypokinetic disease

32
Q

Akinesia/Bradykinesia: without (difficulty initiating) movement/ slowness of movement

A

Hypokinetic Disorder

33
Q

Parkinson’s Disease

A

Rigidity: increase in muscle tone

34
Q

Resting tremor:

A

rhythmic involuntary movement at rest

in Parkinson’s Disease

35
Q

Hypokinetic Disorder like parkinsons dispkay

A

Postural instability

36
Q

Chorea:

A

rapid, abrupt and random movements (limbs, face)

Hyperkinetic Disorders

37
Q

Putamen

A

input from motor and somatosensory cortices

influences motor output.

38
Q

info from limbic cortex, hippocampus and amygdala

A

N. Accumben

39
Q

emotional and behavioral functions.

A

N. Accumbens

40
Q

Athetosis:

A

slow, writhing movements

Hyperkinetic Disorders

41
Q

Hyperkinetic Disorders

A

Types of abnormal involuntary movements

42
Q

Ballism(“ballistic movement ”)

A

:violent, large-amplitude mvmts

hyperkinetic disease

43
Q

Huntington’s Disease (HD

A

progressive degeneration of projection neurons and local circuit neurons in the caudate and putamen.

44
Q

TF in huntington;s disease a Hyperkinetic Disorders;

Neurons that give rise to the indirect pathway are preferentially lost.

A

F Neurons that give rise to the indirect pathway are preferentially lost.

45
Q

extensive —– projections to the striatum;

A

extensive cortical projections to the striatum;

46
Q

recivees info from cortical association areas and has a role in cognitive functions

A

Caudate

50
Q
A
51
Q

cognitive functions

A

Dorsolateral prefrontal Loop:

52
Q

motor output.

A

motor loop

53
Q

Orbitofrontal loop:

A

planning and initiating socially appropriate actions

54
Q

Limbic loop

A

emotional and behavioral functions.

55
Q

Oculomotor loop:

A

control of orientation and gaze.