Basal Ganglia Movement Pathology Flashcards
7 positive signs
- Resting Tremor
- Rigidity
- Chorea
- Dyskinesia
- Dystonia
- Athetosis
- Ballism
Rhythmic oscillations
Resting Tremor
Continuous, Rapid movements
Chorea
Degeneration of caudate nucleus
Huntington’s disease
Involuntary movement during voluntary activation
Dyskinesia
Involuntary sustained muscle contraction
Dystonia
Writhing movements
Athetosis
Fast movements of whole limbs
What is it caused by
Ballism
Lesion of Contralateral Subthalamic nuclei
Hypokinetic Symptom of Parkinson’s disease caused by
Substantia Nigra compacta degeneration, causing less dopamine production reducing mvmt.
Hyperkinetic symptom of Parkinson’s Disease Caused by
Pedunculopontine nuclei degeneration causing less AcH production leading to increased postural activation
2 Signs of Parkinsons
Hypokinetic
And Hyperkinetic
Tx for Parkinsons
L-Dopa
Deep brain stimulation
Optokinetic triggering for smooth mvt pattern
Huntington’s Disease caused by
Degeneriation of Striatum causing decreased inhibition of thalamus resulting in excess mvt. Output
2 types of Dystonia
Genetic and Acquired