Basal Ganglia and Dopamine Pathways Flashcards
The _____ are a group of interconnected nuclei linked to the thalamus in the base of the brain and involved in coordination of movement, and are part of the extrapyramidal motor system.
Basal ganglia
Pyramidal motor system is (hierarchical OR non-hierarchical)?
Hierarchical
Extrapyramidal motor system is (hierarchical OR non-hierarchical)?
Non-hierarchical
Pyramidal and extrapyramidal motor system are independent.
FALSE!
A lesion in the (pyramidal motor system OR extrapyramidal motor system) results in paralysis and spasticity.
Pyramidal motor system
A lesion in the (pyramidal motor system OR extrapyramidal motor system) results in involuntary movements, muscular rigidity, and immobility.
Extrapyramidal motor system
Lesion of the ____ dopamine system results in Parkinsonian syndrome.
Nigrostriatal
Parkinson’s disease is a ____ disorder.
A. Hypokinetic
B. Hyperkinetic
A. Hypokinetic
Huntington’s disease is a _____ disorder.
A. Hypokinetic
B. Hyperkinetic
B. Hyperkinetic
Parkinson’s disease results in ______.
A. Hyperkinetic and hypertonic motor symptoms.
B. Hyperkinetic and hypotonic motor symptoms.
C. Hypokinetic and hypotonic motor symptoms.
D. Hypokinetic and hypertonic motor symptoms.
D. Hypokinetic and hypertonic motor symptoms.
Huntington’s disease results in ______.
A. Hyperkinetic and hypertonic motor symptoms.
B. Hyperkinetic and hypotonic motor symptoms.
C. Hypokinetic and hypotonic motor symptoms.
D. Hypokinetic and hypertonic motor symptoms.
B. Hyperkinetic and hypotonic motor symptoms.
________ has decreased basal ganglia output and increased excitatory input to cortex.
A. Huntington’s disease
B. Parkinson’s disease
A. Huntington’s disease
________ has increased basal ganglia output and decreased excitatory input to cortex.
A. Huntington’s disease
B. Parkinson’s disease
B. Parkinson’s disease
This disease is an inherited genetic disorder that occurs earlier in life.
A. Huntington’s disease
B. Parkinson’s disease
A. Huntington’s disease
_____ is an inherited genetic disorder that results from damage to lenticular nucleus, is characterized by progressive rigidity and intention tremor, and is associated with hepatic cirrhosis and hepatitis.
Wilson’s disease