Basal Ganglia Flashcards

1
Q

Basal ganglia

A
collection of five subcortical nuclei involved in movement
caudate
putamen
globus pallidus
subthalamic nucleus
substantia nigra
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2
Q

Basic pathway

A

input in from most of cortex

projects back to frontal part of cortex through the thalamus

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3
Q

Most input to the basal ganglia is received in the _

A

striatum (caudate + putamen)

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4
Q

Most projections from striatum are to _

A

globus pallidus and substantia nigra

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5
Q

Lenticular nucleus

A

globus pallidus and putamen

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6
Q

Functional divisions of globus pallidus

A
internal segment (GPi)
external segment (GPe)
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7
Q

Two parts of substantia nigra

A
pars compacta (SNc)
pars reticulata (SNr)
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8
Q

Main projections of the basal ganglia to the thalamus come from the _ and reach the _

A

GPi and SNr

VL and VA

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9
Q

Two pathways from struatum to GPi

A

direct pathway

indirect pathway

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10
Q

Ansa leticularis

A

thick fibre bundle

conveys info from GPi to motor thalamus

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11
Q

Lenticular fasciculus

A

conveys info from caudal side of globus pallidus to the VA/VL nuclei of the thalamus

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12
Q

Thalamic fasciculus

A

bundle of fibres headed for the VA/VL of the thalamus

includes ansa fasciculus, lenticular fasciculus and other cerebellothalamic fibres

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13
Q

Four cortic-basal loops

A

Motor
Cognitive
Limbic
Occulomotor

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14
Q

Basal ganglia affect the ipsa- or contra-lateral motor cortex/movements of the body

A

Ipsalateral motor cortex

therefore contralateral movements of the body

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15
Q

Consequence of the direct pathway

A

increase in excitatory drive from thalamus to cortex

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16
Q

NT in projections from cortex to striatum

A

Glu

17
Q

NT in projections from striatum to GPi

A

GABA

18
Q

NT in projections from GPi to VA/VL

A

GABA

19
Q

Direct pathway (main function)

A

Allowing execution of movements by disinhibiting the thalamus

20
Q

Indirect pathway (main function)

A

Prevention of movements