Basal Ganglia Flashcards
*Basal Ganglia
Large masses of grey matter situated in the basal part of the white matter core of each cerebral hemisphere lateral to the thalamus
Functions of Basal nuclei
- Planning and programming of voluntary movements
- Determine how rapidly a movement is to be performed and how large the movement must be
- Decrease muscle tone and inhibit unwanted muscular activity
- Regulate muscle tone and thus helps in smoothening the voluntary motor activities of the body
- Control automatic associated movements, like swinging of arms during walking
- Control group of movements for emotional expression
- Control reflex muscular activities
Corpus Striatum consist of
- Caudate nucleus
- Lentiform nucleus (Putamen + Globus Pallidus)
Lentiform nucleus consist of
- Putamen
- Globus Pallidus
Name the reason for Parkinsons
due to deficiency of the neurotransmitter
dopamine in the corpus striatum following a lesion in substantia nigra and/or its
projections (i.e. nigrostriate fibres)
Symptoms of Parkinsons
Resting tremors
Pill-rolling movements of hands
Lead-pipe or cogwheel type of muscular rigidity
Mask-like face or loss of facial expression
Stiff, shuffling gait
Stooped-posture
Bradykinesia
Characteristic features of Parkinsonism
The 4 cardinal symptoms are tremor, rigidity, Bradykinesia and postural instability
*Chorea
This is characterized by quick, jerky, irregular purposeless involuntary movements, which involve primarily,
the tongue, face and limbs
*Ballismus
Usually results due to vascular lesion of the subthalamic nucleus where normal smooth movements of different parts of the body are integrated
Characterized by a violent burst of irregular movements in the trunk, girdles and proximal extremities