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DD Unit III > Bacterial Toxins > Flashcards

Bacterial Toxins Flashcards

1
Q

Define exotoxin

A

Protein secreted by bacteria

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2
Q

Define endotoxin

A

gram - bacteria, toxicity associated with LPS

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3
Q

What is the mechanism of hyaluronidase, collagenase, elastase, deoxyribonuclease, and streptokinase?

A

Facilitate spread of microbes through tissue

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4
Q

Which toxins facilitate spread of microbes through tissue?

A

hyaluronidase, collagenase, elastase, deoxyribonuclease, and streptokinase

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5
Q

What is the mechanism of pore-forming toxins?

A

Damage cellular membrane (hemolysins, cytolysins)

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6
Q

Which toxins stimulate cytokine production?

A

Superantigens

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7
Q

What is the mechanism of diptheria toxin?

A

Inhibit protein synthesis

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8
Q

What is the mechanism of heat-labile enterotoxins of E. coli & V. cholerae?

A

Modify intracellular signaling pathways (bacteriostatic)

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9
Q

What is the mechanism of shiga toxins?

A

Inhibit protein synthesis

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10
Q

What is the mechanism of pertussis toxin?

A

Modify intracellular signaling pathways

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11
Q

What is the mechanism of heat-stable enterotoxin of E. coli?

A

Modify intracellular signaling pathways

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12
Q

What are the mechanisms of C. difficile toxins A & B?

A

Modify intracellular signaling pathways

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13
Q

What is the mechanism of Anthrax Lethal Factor?

A

Modify intracellular signaling pathways

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14
Q

What is the mechanism of Botulinum toxin?

A

Inhibit NT release

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15
Q

What is the mechanism of Anthrax edema factor?

A

Modify intracellular signaling pathways

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16
Q

What is the mechanism of Tetanus toxin?

A

Inhibit NT release

DD Unit III (2 decks)

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