bacterial pneumonia 1 Flashcards

1
Q

P. aeruginosa gram and shape and oxidase

A

gram (-) rods. oxidase +

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2
Q

P. aeruginosa metabolism

A

strict aerobes, nonfermenting

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3
Q

what does P. aeruginosa produce that distinguishes it from others?

A

pyocyanin and pyoverdin. this makes the colony look green. also has a glycocalyx

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4
Q

where do we find P. aeruginosa

A

usually free living in the environment but can be found as normal flora or opportunistic

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5
Q

what are the growth requirements for P. aeruginosa

A

minimal. it is also resistant to detergents and disinfectants. very easy to culture.

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6
Q

is P. aeruginosa antibiotic resistant.

A

extremely

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7
Q

how is P. aeruginosa contracted?

A

nosocomial, burns, CF, immunocompromised, catheters, IVs, neonates.

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8
Q

most common sites of infection for P. aeruginosa

A

nosocomial UTI, CF pneumonia, burns, neonate or immunocompromised.

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9
Q

rare community acquired P. aeruginosa

A

endocarditis in IV drugs, folliculitis in hot tubs, osteochondritis from sneaker puncture. corneal infection from contact users.

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10
Q

what labs for P. aeruginosa

A

culture aerobic and anaerobic

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11
Q

what to look for when looking for P. aeruginosa

A

look for pigments, metallic sheen and fruity aroma.

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12
Q

treatment for P. aeruginosa infections

A

need to test for sensitivity, but start ab’s immediately. remove catheters and IV.

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13
Q

B. cepacia characteristics

A

similar to P. aeruginosa but much less pathogenic. less able to infect previously healthy patients. No pyocyanin.

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14
Q

B. cepacia growth?

A

readily grows! highly resistant.

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15
Q

who is most at risk for B. cepacia

A

CF patients! this is the leading cause of CF pneumonia. and forms outbreaks in the CF community.

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16
Q

B. cepacia syndrome

A

accelerated pulmonary course with rapidly-fatal bacteremia

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17
Q

what else is B. cepacia responsible for?

A

IV-assocaited septicemia, catheter associated UTI, wound infections, foot rot in swamp deployed.

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18
Q

treatment for B. cepacia for previous healthy?

A

none.

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19
Q

treatment for B. cepacia in CF, Cancer, HIV?

A

need exotic antibiotics.

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20
Q

are there vaccines for B. cepacia

A

only experimental for CF patients.

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21
Q

B. pseudomallei characteristics

A

similar to aeruginosa. this is developing nation, veterinary disease: melioidosis

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22
Q

how is B. pseudomallei transmitted?

A

contact with contaminated water, soil

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23
Q

is B. pseudomallei transmitted human to human?

A

rarely.

24
Q

what are the symptoms of B. pseudomallei

A

flulike, muscle tightness and photosensitivity. can progress from acute local infection to septicemia with abscess in all organs. fatal in 7-10 days.

25
Q

how to diagnose B. pseudomallei

A

culture and gram stain urine, blood, skin lesions. it has a wrinkled colony morphology. PCR and IF tests exist but not normally needed or used. there is usually an abnormal CXR

26
Q

treatment for B. pseudomallei

A

longterm ceftazidimine

27
Q

B. mallei characteristics

A

similar to aeruginosa. nonmotile.

28
Q

what is the reservoir for B. mallei

A

animals. not environmental.

29
Q

who gets B. mallei

A

developing nations veterinary disease. GLANDERS.

30
Q

what is B. mallei/glanders

A

this is a rare zoonosis that is transmitted through animal discharge crossing into damaged skin

31
Q

is B. mallei human to human transmissible?

A

RARE

32
Q

what are the initial symptoms of B. mallei

A

flulike. but can progress.

33
Q

acute localized infection of B. mallei

A

nodules at infection site

34
Q

acute pulmonary B. mallei

A

bronchitis, pneumonia

35
Q

acute septicemia B. mallei

A

fulminant, multi organ disease.

36
Q

chronic B. mallei infection

A

this is farcy.

37
Q

diagnosing B. mallei

A

initially presents as flulike, nodules, bronchitis. septicemia has flushing, cyanosis, disseminated pustules.

38
Q

labs for B. mallei

A

culture and gram stain blood, urine, skin lesions. PCR and IF exist but not commonly used.

39
Q

treatment for B. mallei

A

long term amoxicillin and clavulanate. this is reportable to CDC FBI

40
Q

chlamydia pneumonia characteristics (organisms)

A

there are three organisms C. pneumoniae, C psittaci, C trachomatis. all are slightly different

41
Q

C. pneumoniae feels like what to the patient? does it feel serious to them?

A

mild or asymptomatic cold like normal infection. this may present as long duration cold that progresses to pneumonia

42
Q

C. pneumoniae on exam

A

rales, ronchi, fever, HA.

43
Q

C. pneumoniae labs

A

MIF antibody test. serology and CXR

44
Q

what will the CXR show for C. pneumoniae

A

single sub segmental infiltrate.

45
Q

treatment for C. pneumoniae

A

doxy, or erythmycin, azithromycin, clarithromycin, telithromycin

46
Q

C. psittaci found and spread

A

bird-borne. rare airborne zoonosis

47
Q

C. pneumoniae found and spread?

A

community acquired, human-borne.

48
Q

C. psittaci symptomology

A

abrupt onset, may range from asymp. to severe pneumonia. can progress to meningitis, encephalitis, endocarditis.

49
Q

diagnosis of C. psittaci

A

high fever, nonproductive cough, chest pain, splenomegaly, border spots, and history of exposure to birds.

50
Q

labs for C. psittaci

A

CF or MIF. serology. CXR consolidation in single lower lobe.

51
Q

treatment of C. psittaci

A

tetracycline or doxy. or erythromycin

52
Q

c. trachomatis found?

A

infection at birth

53
Q

c. trachomatis pathogenesis

A

birth infected infant or severely immunocompromised adult.

54
Q

c. trachomatis diagnosis

A

nasal obstruction and discharge. conjunctivitis, middle ear abnormality. crackles.

55
Q

labs for c. trachomatis

A

swab, culture or hybridization. bilateral interstitial infiltrates and hyperinflation.

56
Q

treatment for c. trachomatis

A

oral erythromycin