Bacterial Pathogen II Flashcards
virulence factors (excreted or not) are
toxic to human or animal orplant cells
virulence factors :Type I
bind and act at host cell surface
virulence factors : Type II
act on host cell membranes
virulence factors : Type III
A-B type toxins, includes signlechain and multisubunit toxins
other ways to categorize toxin
- non protein and protein toxins
- endotoxin versus exotoxin
- effector proteins
superantigens bind
class II MHC outside the peptide cleft
Staph aureus is gram
positive
Stap aureus can cause
food posining bacteremia/sepsis toxic shock syndrome abscesses cellulities
quorum sensing allows bacteria to
communicate with one another and act in groups
quorum: gram neg
Acyl homoserine
quorum: gram pos
circularized peptides
Agr two component system
AgrC = sensor kinase AgrA = Respnse Regulator
Hammamelitannin from witch hazel, inhibits
MRSA quorum sensing
Quorum sensing, bacterial pathogen can also sense
hormones produced by host
what hydrolyzes the lipid lecithin and contributes to gangrene?
phospholipases
