bacterial 2 Flashcards
Toxic Shock Syndrome
50% of nonmenstrual
cases
menstrual cases
Enterotoxins B and C
TSST-1 (TSS toxin 1)
Staphylococcal Scalded
Skin Syndrom
Exfoliative
toxins
bind to
Epidermolytic
toxins A and B (ET-A,
ET-B)
desmoglein-1
Children under 5
years of age, adults
with renal failure or
immunodeficiency risk of
Staphylococcal Scalded
Skin Syndrome
Positive Nikolsky’s
sign
•in lesional and
non-lesional skin
Staphylococcal Scalded
Skin Syndrome cleavage
Subgranular blister
Exfoliative toxins A
and B
• TSST-1
Staphylococcal Scalded
Skin Syndrome
Bullous Impetigo
SSSS VS BI
site of staph infx
cleavage
•BI Subcorneal blister, AT SITE VS DISTANT
(Staphylococcal Scarlet
Fever) VS SCARLET FEVER??
Generalized scarlatiniform rash
• No other signs
of Scarlet Fever
signs of Scarlet Fever
Pastia’s lines,
pharyngitis,
strawberry tongue
circumoral pallor
Sycosis barbae
StaphylococcaL
Ecthyma
majority of cases caused by Group A
streptococcus)
StaphylococcaL
Botryomyosis
S. aureus
E. coli
Proteus species
P. aeruginosa
staphylococcal whitlow
Felon
Purpura fulminan
staphylococca
Sharply demarcated tender erythematous plaque in perianal region in children
Perianal streptococcal “cellulitis”
Scarlet Fever
TOXIN
• Pyrogenic exotoxin (erythrogenic toxin) – mediated: types A, B, and C
Purpura Fulminans
leading association
most common site
• Group A streptococcal infection
extermities ear and nose
Corynebacterium tenuis causes
• Characteristic features:
Trichomycosis Axillaris
Yellowish brown concretions on axillary hair shafts
Francisella tularensis
caused by contact with
Tularemia infected rabbits (e.g., hunters)
SCARLET FEVER
Enanthem
Exanthem:
: Exudative pharyngitis, strawberry tongue
Diffuse erythematous eruption with “sandpaper” texture, beginning on head
and neck, and then generalizes, sparing palms/soles
• Desquamation upon resolution of exanthem, beginning on face/ears
Pastia’s lines
linearbpetechial patches in axillae and antecubital fossae
Tularemia
most common
Other forms: Glandular, chancriform, oculoglandular, typhoidal, pulmonary, oropharyngeal,and meningeal
• Treatment:
Ulceroglandular form – chancre raised borders and
regional lymphadenopathy finger or hand
Tularemia treatment
Streptomycin
