Bacteria of the Respiratory Tract - Extra Review Cards Flashcards
G+ or G- ?
Bordetella pertussis
G-
G+ or G- ?
Corynebacterium diphtheriae
G+
G+ or G- ?
Neisseria meningitidis
G-
G+ or G- ?
Streptococcus pyogenes
G+
G+ or G- ?
Staphylococcus aureus
G+
G+ or G- ?
Streptococcus pneumoniae
G+
G+ or G- ?
Haemophilus influenzae
G-
G+ or G- ?
Mycoplasma pneumoniae
neither
G+ or G- ?
Pseudomonas aeruguinosa
G-
G+ or G- ?
Legionella pneumoniae
G-
G+ or G- ?
Mycoplasma tuberculosis
G+ (technically correct… the best kind of correct)
Vaccine against A, C, Y, W135 serovars
Neisseria meningitidis
Three phases of whooping cough?
What is the pathogen?
catarrhal -> paroxysmal -> convalescence
Bordetella pertussis
PTx blocks Gi_alpha, FHA and pertactin
Bordetella pertussis
Does bordetella pertussis have a vaccine?
Against what?
Yes
PTx (pertussis toxin) and pertactin
G+coccobacillus in ‘Chinese character’ arrangement
Corynebacterium diphtheria
G+, “positive everything”
Staphylococcus aureus
pseudomembranes
Corynebacterium diphtheria
Beta-hemolytic, catalase(-), M-proteins, ASO
Streptococcus pyogenes
What does diphtheria toxin (DTx) do?
Blocks EF2
Name (2) virulence factors of S. pyogenes
M-protein, ASO
A-protein
Staphylococcus aureus
(2) Diseases causes by S. pyogenes
strep throat, scarlet fever
(2) virulence factors of S. pneumoniae
pneumolysin, IgA protease
23-valent and 13-valent vaccines available
Which one is for children?
S. pneumoniae
13-valent for children, 23-valent for adults
Does H. influenzae have a vaccine?
Yes. But Hib only.
Major diseases caused by S. pneumoniae
Lobar pneumonia, sinusitis, otitis media
Target of the diphtheria vaccine?
DTx (toxin)
What grows primarily on chocalte agar?
What is chocolate agar?
Haemophilus influenzae
chocolate agar = Heme/NAD
ox+, forms biolfilms
Pseudomonas aeruguinosa
(2) major virulence factors of H. influenzae
OMPs and LOS
Morphological characteristics of Mycoplasma pneumoniae
What causes disease with this bug?
Very small, pseudomorphic, ‘fried egg’
Attaches between cilia in respiratory epithelium (via P1 adhesin) -> metabolites trigger an inflammatory reaction -> inflammatory cytokines damage respiratory epithelia
What is P1 adhesin? What uses it?
Virulence factor used by Mycoplasma pneumoniae to attach to the respiratory epithelium.
Which (2) pathogens have possess a single cilia?
Pseudomonas, Legionella
Legionella - where is it found?
What diseases does it cause? Which one is worse?
Water supplies
Legionnaire’s disease >> Pontiac fever
What generally only grows on buffered charcoal?
Pseudomonas aeruguinosa
alpha-hemolysis?
S. pneumoniae
What is cord factor? What uses it?
Virulence factor used by Mycoplasma tuberculosis to block PMNs.
Acid fast? Why?
Mycoplasma tuberculosis, due to mycolic acids in its cell wal
Intracellular opportunist that causes Pontiac Fever?
Legionella pneumoniae
Name (2) general virulence strategies employed by Pseudomonas
Forms biofilms
Toxins
Commonly found with cystic fibrosis
Pseudomonas aeruguinosa
Diseases caused by H. influenzae
pneumonia, sinusitis, otitis media, epiglottitis
(2) bugs that cause atypical pneumonia
Mycoplasma pneumoniae
Pseudomonas aeruguinosa
G-, ox+, cat+
G+, ox+, cat+
Neisseria meningitidis
Staphylococcus aureus
“Positive Everything”
S. aureus