Bacteria I

Question 1

What are the acid-fast positive infectious organisms?

Answer 1

Cryptosporidium (protozoan)
Mycobacteria (Mycobacterium Tb)
Mycoplasma
Nocardia

NoCAMM

Question 2

FtsZ role in binary fission

Answer 2

Makes contractile ring for splitting dividing bacterium into 2 bacterium

Question 3

Process of bacterial gene transfer where bacteria take up naked fragments of DNA (usually from lysed cells) and incorporate them into their genomes

Answer 3

Transformation

Transform into me man, pick things up along the way - learn lessons along the way

Question 4

Process by which there is one way transfer of plasmid or genomic DNA from a donor to a recipient thru a sex pilus

Answer 4

Conjugation

Consummation - sex

Question 5

Genetic transfer mediated by bacterial viruses (bacteriophages)

Viruses pick up fragment of DNA derived from one bacterium, package them, then infect other bacteria and then deliver the DNA into the infected cells

Answer 5

Transduction

Question 6

2 bacterial spores & the typical protozoan spore

Answer 6

Clostridia (Bacteria)
Bacillus (Bacteria)
Cryptosporidium (protozoan)

Question 7

1. Bacteria growth in presence of air
2. Bacterial growth in absence of air
3. Bacteria that can grow in both presence or absence of oxygen

Answer 7

1. Aerobic growth
2. Anaerobic growth
3. Facultative anaerobes

Question 8

Growth that is best under low oxygen concentration compared to atmospheric oxygen levels

Answer 8

Microaerophilic growth

Question 9

Patients with cystic fibrosis are more susceptible to infection by which of the following?

A. H flu
B. Cryptosporidium
C. Pseudomonas aeruginosa
D. Bored tells pertussis

Answer 9

C. Pseudomonas aeruginosa

Question 10

How does Pseudemonas aeruginosa outcompete Staph aureus in cystic fibrosis patients?

Answer 10

Pseudemonas drives S. Aureus into anaerobic metabolism, slowing the growth of S. Aureus.

This allows Pseudemonas to perform “Fe grabbing mechanism” and use iron to accelerate its own growth…thus outcompeting S. Aureus

Pseudemonas ability to steal Fe is a virulence factor

Question 11

Inhibitors of cell wall biosynthesis

Answer 11

Penicillin and penicillin-like drugs

Question 12

Protein synthesis inhibitors

Answer 12

Aminoglycosides

Tetracyclines

Question 13

DNA synthesis inhibitors

Answer 13

Quinolones

Metronidazole

Question 14

Antimetabolite-type anti microbial

Answer 14

Sulfonamide