BACTERIA AND ANTIBIOTICS Flashcards
1
Q
What are the two broad types of antibiotic in terms of mechanism of action?
A
Bacteriostatic
Bactericidal
2
Q
Are penicillins bacteriostatic or bacteriocidal? What is the mechanism of action for penicillins?
A
Bactericidal
They possess a thiazolidine ring connected to a beta-lactam. This ring interacts with and inhibits the repair of bacteria cell wall. The result is lysis.
3
Q
Do penicillins work on gram positive and gram negative bacteria?
A
Yes, unless resistance has developed.
4
Q
Give some examples of penicillin antibiotics.
A
Benzylpenicillin Penicillin V Ampicillin (Broad spectrum) Amoxicillin (Broad spectrum) Methicillin (β-lactamase-resistant) Flucloxacillin (β-lactamase-resistant) Dicloxacillin (β-lactamase-resistant) Piperacillin
5
Q
What are the broad spectrum penicillins?
A
Ampicillin
Amoxicillin