Bact Final Flashcards
T/F The majority of bacteria are intracellular pathogens.
False.
Most bacteria are extracellular pathogens
Intracellular pathogens: Rickettsia, Anaplasma, Chlamydia, Lawsonia, and Clostridium piliforme
Whish bacteria are facultative intracellular bacteria?
Mycobacterium, Rhodococcus
they can be extracellular or intracellular
what is the sequence of events of bacterial pathogenesis?
entry into host evade host defense colonize host systems multiply exert damage in host transmit to other hosts- become infectious
What bacterial structures enhance virulence and what do they do?
Flagella: locomotion/motility; endoflagella in spirochetes Fimbriae/Pili: adherence Capsule: evade phagocytosis Spores: environmental survival Toxins: endotoxins/exotoxins
What are the gram + cocci families?
Staphlococcus
Streptococcus
Enterococcus
Micrococcus
What are the gram + rods?
Listeria Erysipelothrix Bacillus Actinomyces Trueperella Dermatophilus Clostridium (anaerobic) Corynebacterium Rhodococcus Mycobacterium
What are the acid fast bacteria?
Mycobacterium
Partial acid fast: Corynebacterium, Rhodococcus, Nocardia, Mycobacterium
What are the gram - cocci?
False. Gram - cocci are not common clinical isolates
what are the gram - anaerobes?
Fusobacterium
Bacteroides
Dichelobacter
What are the spirochetes? (gram -)
Brachysira
Borrelia
Leptospira
Treponema
Which bacteria are microaerophilic? (also gram -)
Campylobacter
Helicobacter
Lawsonia
Which fungi are dimorphic?
Blastomyces
Histoplasma
Coccidioides
Sporothrix
What 2 antimicrobial susceptibility tests are there?
Disk diffusion (Kirby Bauer) Broth/Agar dilution
What is MIC?
Minimum inhibitory concentration.
The minimum amount of drug required to inhibit bacterial growth
What is Griseofulvin?
Antifungal. Inhibits mitosis, used only for dermatophytes, is only PO and teratogenic in cats
What are Polyenes?
Amphoterocin B, Natamycin and Nystatin.
Antifungals that inhibit ergosterol
What is Flucytosine?
Antifungal that inhibits nucleic acid synthesis
What are Allylamines?
Terbinafine, antifungal that inhibits ergosterol.
What is pyoderma?
Pyogenic bacterial infection of the skin. Can be superficial, surface or deep
What is the most common Staph. isolate in canine skin disease?
S. pseudintermedius
If a Staph. isolate is macrolide (erythromycin) resistant, can you use clindamycin to tx?
No. all Staph. that are macrolide resistant are considered clindamycin resistant unless otherwise confirmed by a D-test
What bacteria causes ‘Greasy pig disease’?
Staph. hyicus
MDx: exudative epidermitis
What bacteria causes ‘bumble-foot’?
Staph. aureus
What bacteria causes botryomycosis?
S. aureus- in rodents, people and horses
What is a common isolate in feline lymph node abscesses?
Yersinia pestis
What causes feline leprosy?
Mycobacterium lepraenium