B9 Cancer Epidemiology Flashcards

1
Q

Define incidence

A

the number of new cases of a disease that occur during a specific time period in a defined population

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2
Q

Define prevalence

A

the number of ongoing cases of disease in a population at a specific point

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3
Q

What is the risk in males and females of developing cancer before the age of 75?

A

Males - 21%

Females - 17%

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4
Q

What is the risk of dying from cancer before age of 75 for males and females?

A

Males -13%

Females 9%

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5
Q

What are the top 3 most common cancers worldwide?

A
  1. Lung
  2. Breast
  3. Bowel/colorectal
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6
Q

What are the top 3 most common cancers in FEMALES?

A
  1. Breast
  2. Lung
  3. Bowel
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7
Q

What are the top 3 most common cancers in MALES?

A
  1. Prostate
  2. lung
  3. Bowel
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8
Q

What is meant by (environmental) risk transition?

A

the process by which traditional communities with associated environmental health issues become more economically developed and experience new health issues. - e.g. developed countries have higher incident of colorectal cancer probably due to diet change

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9
Q

Name some of the reasons why cancer is more prevalent in developed countries

A

Ageing population due to:

  • improvements in medical care
  • public health interventions (e.g. vaccination, clean water)
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10
Q

Name the top 3 cancers that have the highest 10yr survival rates

A
  1. Testicular cancer
  2. malignant melanoma
  3. Prostate
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11
Q

Name the top 3 cancers that have the highest 5yr survival rate

A
  1. testicular cancer
  2. malignant melanoma
  3. breast cancer
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12
Q

Name the 3 cancers with the lowest 10 yr survival rate

A
  1. Pancreatic cancer (lowerst)
  2. lung cancer
  3. Brain tumours/oesophageal cancer
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13
Q

what percentage of children diagnosed with childhood cancers are likely to survive more than 5yrs?

A

85%

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14
Q

Rougley how many cases of childhood cancer are diagnosed in UK each year

A

~1,400

<1% of total malignancies

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15
Q

What are the 3 most common cancers children get?

A
  1. leukaemias
  2. Brain and CNS tumours
  3. Lymphomas
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16
Q

Is survival of childhood cancer generally better or worse than adult cancers?

A

Better

17
Q

How can descriptive epidemiology help to work out what causes childhood cancer?

A

Help identify global differences in incidence patterns to aid in identifying causes.

18
Q

What are some known causes of cancer?

A
  • infections (HPV, H.pylori, HIV, EBV)
  • Radiation
  • Lifestyle (diet, obesity, alcohol, tobacco)
  • occupational
  • hormonal
  • genetics
19
Q

What cancer canHep B virus cause?

A

Liver cancer

20
Q

What percentage of cancers is tobacco associated with?

A

50-60%

21
Q

What cancers is smoking/tobacco causally linked to?

A

lung, upper resp. tract, oesphagus, bladder, pancreas

22
Q

one genetic mutation contributes what percentage to cancer incidence?

A

0.1% or less

23
Q

What are susceptibility genes?

A

genetic variants that make an individual more susceptibe to certain types of cancer

24
Q

What is the aim of primary prevention

A

to reduce exposure to carcinogens - Legal and lifestyle changes

25
Q

What is the aim of secondary prevention

A

Aims to identify those with pre-clinical disease to influence progression of disease- e.g. screening

26
Q

What is tertiary prevention?

A

Aims to modify the outcomes of disease - improve treatments and improve quality of life