B7.070 Antidepressants and ASD Flashcards
null hypothesis
outcome(exposed) = outcome(unexposed)
risk ratio
risk in exposed group/ risk in unexposed group
RR > 1
exposure is harmful (risk increases)
RR < 1
exposure is protective (risk reduction)
relative risk increase
RR - 1 = relative risk increase
absolute risk increase
risk in exposed group - risk in unexposed group
number needed to treat/harm
1 / absolute risk increase
hazard ratio
measure of association comparing outcome incidence and outcome timing between exposed and unexposed groups
logistic regression
outcome data in categories (yes/no)
linear regression
outcome data continuous (weight)
internal validity
how well was the study conducted
external validity
are the results generalizable
clinical importance of a study
NNT/NNH
risk vs benefit