B5.066 - Exocrine Pancreas

Question 1

what does the pancreas do

Answer 1

makes enzymes that help you digest food. Normally those enzymes flow through a small opening into your small intestine

Question 2

what are acinar cells

Answer 2

exocrine cells pancreas that produce and tranpsort enzymes passed into duodenum to help digest food

Question 3

duct cells (centroacinar)

Answer 3

spindle shaped extension of intercalated duct cells into each pancretic acinus

intercalated ducts take bicarb to intralobular ducts which become lobular ducts which converge to form main pancreatic duct

Question 4

regulation of exocrine pancreas

Answer 4

regulated by neural reflexes, GI hormones, absorbed nutrients

Question 5

in absence of proper pancreatic secretion wht happens

Answer 5

maldigestion and malabsorption of nutrients may cause malnutrition and associated complications

Question 6

digestive enzymes

Answer 6

secreted by acinar cells

amylytic, lipolytic, proteolytic, ribonucleases

Question 7

zymogens and proenzymes

Answer 7

zymogens - trypsinogen, chymotrypsinogen

proenzymes - procarboxypeptidase, proelastase

Question 8

what do amylase and lipase do

Answer 8

amylase - digests carbs and starches into di and trisaccharides to glucose

lipase - fats into fatty acids and cholesterol

Question 9

describe pancreatic secretions

Answer 9

chyme contact with intestinal mucosa and bile acids

enteropeptidase/kinase activated to convert trypsinogen to trypsin

trypsin activates other zymogens and proenzymes to breakdown proteins