B4.051 - Acid Base Balance and Ventilation Prework 1 Flashcards
what is normal PaO2
95
what is normal PaCO2
40
what is normal pH
7.4
what is normal HCO3-
24
what factors stimulate alveolar ventilation
decreased PaO2
increased PaCO2
Decreased arterial pH
how long does metabolic compensation take to develop in the setting of respiratory acid base disturbances
several days
how long does it take for respiratory compenation to occur in the setting of a metabolic acid base disturbance
it occurs very rapidly
what is the slope of the plasma buffer curve
-10 mmol HCO3- per pH unit
describe how the change in PaCO2 changes pH
each change in 10 mmHg PaCO2 causes a change in pH of .08
if PaCO2 increases by 20 mmHg due to alveolar hypoventilation acutely what happens to arterial pH
decreases by .16
asthma attack for example
if PaCO2 is increased due to COPD what will the pH be
higher than 7.24 because of metabolic compensation
this is a chronic condition
if PaCO2 is decreased by 20 mmHg how does this change arterial pH in an acute setting
increases by .16 to 7.56
what is the main form of hydrogen excretion in the body
expiration
how does pH relate to PCO2 and bicarb
pH is directly proportional to bicarbonate concentration and inversely proportional to PCO2
identify the acid base disorder and an example of a cause
Respiratory acidosis
Short term hypoventilation