B4.051 - Acid Base Balance and Ventilation Prework 1 Flashcards

1
Q

what is normal PaO2

A

95

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2
Q

what is normal PaCO2

A

40

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3
Q

what is normal pH

A

7.4

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4
Q

what is normal HCO3-

A

24

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5
Q

what factors stimulate alveolar ventilation

A

decreased PaO2

increased PaCO2

Decreased arterial pH

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6
Q

how long does metabolic compensation take to develop in the setting of respiratory acid base disturbances

A

several days

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7
Q

how long does it take for respiratory compenation to occur in the setting of a metabolic acid base disturbance

A

it occurs very rapidly

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8
Q

what is the slope of the plasma buffer curve

A

-10 mmol HCO3- per pH unit

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9
Q

describe how the change in PaCO2 changes pH

A

each change in 10 mmHg PaCO2 causes a change in pH of .08

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10
Q

if PaCO2 increases by 20 mmHg due to alveolar hypoventilation acutely what happens to arterial pH

A

decreases by .16

asthma attack for example

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11
Q

if PaCO2 is increased due to COPD what will the pH be

A

higher than 7.24 because of metabolic compensation

this is a chronic condition

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12
Q

if PaCO2 is decreased by 20 mmHg how does this change arterial pH in an acute setting

A

increases by .16 to 7.56

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13
Q

what is the main form of hydrogen excretion in the body

A

expiration

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14
Q

how does pH relate to PCO2 and bicarb

A

pH is directly proportional to bicarbonate concentration and inversely proportional to PCO2

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15
Q

identify the acid base disorder and an example of a cause

A

Respiratory acidosis

Short term hypoventilation

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16
Q

identify the acid base disturbance and an example of a cause

A

respiratory acidosis

Metabolic compensation

Prolonged hypoventilation like COPD

17
Q

identify the acid base disturbance and examples of causes

A

respiratory alkalosis

Short term hyperventilation

Anxiety induced hyperventilation, short duration at high altitude

18
Q

identify the acdi base disturbance and some causes

A

respiratory alkalosis

metabolic compensation

Chronic hyperventilation (weeks at high altitude)

19
Q

identify the acid base disturbance and some causes

A

metabolic acidosis

Uncompensated diabetes

Lactic acid production due to shock

20
Q

identify the acid base disturbance and some causes

A

metabolic acidosis

respiratory compensation

21
Q

identify the acid base disturbance and some causes

A

metabolic alkalosis

Loss of gastric acid due to vomiting or nasogastric suction

22
Q

identify the acid base disturbance

A

metabolic alkalosis

respiratory compensation

23
Q

what happens to PaCO2 and HCO3- in compensated and uncompensated respiratory acidosis

A

Uncompensated - PaCO2 increased HCO3- increased slightly

Compensated - PaCO2 increased and HCO3- increased moreso (urine will be acidic)

24
Q

what happens to PaCO2 and HCO3- in compensated and uncompensated metabolic acidosis

A

uncompensated - PaCO2 is normal and HCO3 is decreased

compensated - PaCO2 is decreased due to alveolar hyperventilation and HCO3- is decreased even more

25
Q

what happens to PaCO2 and HCO3- in compensated and uncompensated respiratory alkalosis

A

uncompensated - PaCO2 is decreased and HCO3 - is decreased slightly

compensated - PaCO2 is still decreased and HCO3- is decreased even more due to metabolic compensation (urine will be alkalotic)

26
Q

what happens to PaCO2 and HCO3- in compensated and uncompensated metabolic alkalosis

A

uncompensated - PaCO2 is normal and HCO3- is increased

compensated - PaCO2 is increased due to alveolar hypoventilation and HCO3- is increased even more

27
Q
A
28
Q
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29
Q
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30
Q
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31
Q
A