B3.1 Control systems Flashcards
What is a circadian rhythm?
A biological rhythm that happens over one day
What is the biological clock?
A timing mechanism in the body that helps to control various rhythms, like sleeping and waking
What does melatonin do?
Makes people sleepy
Why does the biological clock need regular exposure to day and night?
To keep it in sync with the 24 hour cycle
Why do flowers open during the daytime?
Because it means that insects can pollinate them
Why do flowers only produce nectar during the day?
Because that is when insects are likely to visit them
What is a response to changing day length called?
Photoperiodism
What is left after a plant dies during winter?
Seeds
What do seeds do as they days get longer during spring?
Germinate
What happens to the growth of plants as days get longer?
It gets faster
What are the poisonous chemicals that lupin produces called?
Alkaloids
Why does lupin produce alkaloids?
To be poisonous to insect pests and large herbivores that might want to eat them
What is a pathogen?
An organism that causes disease
How does potato blight kill potatoes?
It kills their leaves so they are no longer able to photosynthesise and so don’t have any energy for respiration and die
What do some potatoes do in response to potato blight?
They produce chemicals to kill it
What effect does a pathogen destroying or damaging a crop have on humans?
The food supply is at risk and so there could be a famine
What is digoxin?
A chemical found in fox gloves
What medical use can digoxin be used for?
It can be used to treat heart disorders when used in small doses
What are many plant poisons commonly used for?
Making medicinal drugs
What is quinine used for?
Treating the symptoms of malaria
Where is quinine found?
Cinchona trees
What is aspirin produced from?
Willow trees
What is aspirin used for?
Treating symptoms of disease such as pain or fever
What parts of a potato are poisonous?
- the leaves because that’s where poisonous alkaloids are produced
- the tubers if they have been exposed to light and gone green
Who proved that micro organisms were responsible for some diseases and foods going off?
Louis Pasteur
What did Louis Pasteur suggest people do to stop diseases and prevent food from going off?
Keep micro organisms away from people and food
What are aseptic techniques?
The methods used to keep things free from living micro organisms
What is pasteurisation?
The process of briefly heating foods (such as milk) before storing them in order to kill bacteria
What experiment did Louis Pasteur do to prove that micro organisms caused disease and food to go off?
- he put broth in one straight necked flask and one swan necked flask after boiling both for one hour
- the broth in the straight necked flask went off after four days because the bacteria had easy access to the broth
- the broth in the swan necked flask stayed fresh after four days because all the bacteria collected in the swan neck
- this showed that when bacteria had access to the broth it caused it to go off
What three things do bacteria need to grow quickly?
Food, oxygen and warmth
What is exponential growth?
When the growth rate of a population is proportional the population’s current value
What could happen if you drink milk with high levels of bacteria?
It cause infections of the gut such as food poisoning
What is a way of measuring how much bacteria there is in a sample?
Using resazurin dye, as it shows how quickly oxygen is used up. So if there are more bacteria they respire more, so the resazurin is used up more quickly
What are the different colours resazurin can be?
- blue when there is plenty of oxygen
- pink and eventually colourless when oxygen levels fall
Who created the first vaccine?
Edward Jenner
How did Edward Jenner discover vaccines?
He noticed that milk maids didn’t seem to get smallpox,and from this he came to the conclusion that getting cowpox might prevent a person from getting smallpox. To test this he took the pus from a cowpox blister and rubbed it into the skin of a boy called James Phipps, who only got a mild fever. After that he did the same with a smallpox blister, but James didn’t get sick as the cowpox vaccine had made him immune
What are antigens?
Proteins that the immune system recognises as foreign found on the outer surfaces of viruses and cells
How does the immune system destroy foreign viruses and cells?
By recognising foreign antigens and getting antibodies to stick to the pathogen antigens
What does a vaccine contain?
Harmless version of the pathogen a person is vaccinating against
What type of white blood cell respond to a vaccine?
Lymphocytes
What are memory lymphocytes?
Lymphocytes left over from a previous attack on the immune system so that a pathogen can be killed more quickly in case it comes back
What is the immune response?
The way the body responds to infection
What is infection?
The process of an illness being caused by the entry of a pathogen into the body
What is immunisation?
Making someone immune to a disease
How does a vaccine make you immune?
- a weakened pathogen is injected into the body. It has antigens on its surface
- a lymphocyte with an antibody that perfectly fits the antigen is activated
- this lymphocyte divides over and over to produce clones of identical lymphocytes
- these lymphocytes do the following things: some secret large amounts of antibodies, some stick to the antigens and destroy the pathogen and some remain in the blood as memory lymphocytes ready to respond immediately if the same antigen ever turns up again
What can be some side effects of a vaccine?
A mild fever or rash
What may prevent parents from getting their children immunised?
Media scares about the risks of immunisation
What are three risks of immunisation?
- it’s common for a person to get redness or swelling around the site of the vaccination
- some children may get a mild form of the disease they are being vaccinated against
- very rarely a child suffers an allergic reaction
What are three advantages of immunisation?
- a child can become immune to a disease without having to suffer it
- the chances of any long-lasting harm is smaller than if a person actually got measles, mumps, rubella or diphtheria
- if enough children get vaccinated, then it becomes so rare that even unvaccinated children are unlikely to get it
What is a primary response?
The response when a person is infected for the first time
What is the secondary response?
The response after a person is infected a second time when memory lymphocytes are used
What are monoclonal antibodies?
Large quantities of identical antibodies
What is a B lymphocyte?
A lymphocyte that has started producing antibodies and can’t divide anymore
How are monoclonal antibodies produced?
- an antigen is injected into a mouse so that it produces B lymphocytes against it
- myeloma(cancer) cells are grown in a culture medium
- the B lymphocyte cells and the myeloma cells are fused, forming monoclonal antibodies
Why are monoclonal antibodies used?
To make large amounts of divisible B lymphocytes
What is a hybridoma?
A cell produced from the fusion of two other cells (a hybrid of both)
How are monoclonal antibodies used in pregnancy tests?
A dipstick covered in monoclonal antibodies is dipped in urine to see if any HGH, a hormone produced in the urine of pregnant women, is there. If it is, the HGH binds to the monoclonal antibodies on the stick and causes a colour change
Why do radiologists use monoclonal antibodies to tell where any blood clots or cancer cells are?
Monoclonal antibodies can be made slightly radioactive and can bind to the membranes of platelets or cancer cells. This allows radiologists to detect where the platelets or cancer cells are, as the radioactive monoclonal antibodies show up on X-rays
What damage can platelets cause when in the wrong place?
They can cause blood clots in the heart or the brain which can kill a person
What do platelets do?
Cause blood clots
What two things are given to patients to treat cancer?
- ionising radiation (radiotherapy)
- drugs (chemotherapy)
What are the drawbacks of chemotherapy and radiotherapy?
It’s difficult to make sure that only cancer cells are targeted
What are three reasons drugs attached to monoclonal antibodies are useful for treating cancer?
- the drug is only delivered to cells that need to be destroyed
- less of the drug is needed and it isn’t wasted in parts of the body that are healthy
- there is much less risk of harming healthy cells
What are metabolic reactions?
Chemical reactions happening within respiring cells
What waste products do metabolic reactions happening in respiring cells produce?
Carbon dioxide