B2 - Organisation Flashcards
What is a tissue?
A group of similar cells working together to perform a particular function
What is an organ?
A group of different tissues working together to perform a particular function
What is an organ system?
A group of organs with related functions working together to perform a specific function
What is the stomach made up of?
- Muscle = Contracts to churn
- Glandular tissue = Made from cells that secrete chemicals such as enzymes and hormones
- Epithelial tissue = Covers the inside and outside parts of the body
Journey food takes?
Mouth - Oesophagus - Stomach - Small intestine - Large intestine - Rectum - Anus
Complimentary organs or the digestive system?
Salivary glands, liver, gall bladder, pancreas
Function of mouth?
- Mechanical digestion - teeth break down food into smaller pieces to increase SA to volume ratio
- Amylase in saliva starts digesting starch to maltose
Function of the oesophagus?
- Connects mouth to stomach
- Contracts to push food down
Function of stomach?
- Mechanical digestion by churning
- Protease enzymes start to digest proteins
- HCL kills bacteria and gives optimal pH for protease enzymes
Function of small intestine?
Absorption of nutrients and digested food molecules
Function of large intestine?
Water absorption
Function of pancreas?
- Produces amylase, lipase and protease
- Secretes enzymes into small intestine to raise Ph of fluid coming out of the stomach
Function of liver?
- Produces bile to emulsify fats
Function of gall bladder?
Stores bile to release into small intestine as needed
Role of bacteria in digestion?
- Breaking down substances we can’t digest
- Supplying essential nutrients
- Synthesising vitamin K
- Providing competition with harmful bacteria to restrict their growth
What are enzymes?
Biological catalysts made from protein
Why are enzymes specific 3D shapes?
They are formed from protein molecules
How does the lock and key model work?
- Enzymes and substrates move about in a solution
- When an enzyme and it’s complimentary substrate collide, an enzyme-substrate complex forms and the reaction occurs
- A product/products are formed which are released form the active site
What happens to the enzyme after it has been used?
It is unchanged and catalyse further reactions
What is the induced-fit model?
When the substrate and active site change shape slightly to fit more perfectly when they bind
Optimal enzyme temperature in humans?
Around 37 degrees
What is denaturation?
High temperatures will start to break the bonds that hold the enzyme together and it will start to lose its shape. Eventually the active site is lost completely and the substrate cannot bind
Why does increasing temperature up to a point increase enzyme activity?
The molecules have more energy so move faster and the number of collision with substrate molecules increases
What happens at low temperatures?
Denaturation does not occur but there is less kinetic energy so the substrates collide at a lower rate
What is the best pH for enzymes?
Mostly 7 but some are produced in acidic conditions which have a lower optimum pH (stomach) and some that have higher (small intestine)
What can cause denaturation?
Wrong pH or too high temperatures
What is the purpose of digestion?
To break down large, insoluble molecules into smaller, soluble molecules that can be absorbed into the bloodstream
What are three types of digestive enzymes?
Carbohydrases, proteases and lipases
What do carbohydrases do?
Break down carbohydrates into simple sugars
What does amylase do?
A carbohydrase which breaks starch into maltose
Where is amylase made?
Salivary glands, pancreas, small intestine
What do proteases do?
Break down proteins into amino acids in the stomach and small intestine
Where is protease made?
Stomach (pepsin), pancreas and small intestine
What do lipases do?
Break down lipids into glycerol and fatty acids
Where is lipase made?
Pancreas
Where is lipase secreted?
Small intestine (Duodenum)
Roles of bile?
- Neutralise HCl from the stomach because the enzymes in the small intestine have a higher optimum pH
- Emulsifies fats
What is glucose used for in humans?
Some that is released from carbohydrate breakdown is used in respiration to release energy
What are amino acids used for in humans?
To build proteins such as enzymes and antibodies
What are the products of lipid digestion used for?
To build new cell membranes and hormones
How have the lungs adapted for gas exchange?
- Large surface area for faster diffusion
- Thin walls for a short diffusion pathway
- Good ventilation for concentration gradients
- Good blood supply for concentration gradients
Structures of the lungs?
Nasal cavity, trachea, pleural cavity, lung, bronchus, bronchiole, alveoli, intercostal muscle, ribs, diaphragm
Function of the rib?
- Bone structures to surround and protect lungs
- Aid breathing
Function of the intercostal muscles?
Muscles between ribs which control movement, causing inhalation and exhalation
Function of the diaphragm?
Sheet of connective tissue and muscle at the bottom of the thorax that helps change the volume of the thorax
Function of the trachea?
- Windpipe that connects the mouth and nose to the lungs
- Lined with ciliated epithelial cells (to move mucus up to the mouth)
Function of the bronchi?
Tubes branching off the trachea with one for each lung
Function of the bronchioles?
Bronchi split to form smaller tubes called bronchioles that connect to the alveoli