B2 Flashcards

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1
Q

What is bile?

A
  • It is made in the liver.
  • Excess bile is stored in the gall bladder.
  • It helps speed up the digestion of lipids.
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2
Q

What does bile do?

A
  • Converts large lipid droplets into smaller droplets, emulsifying the lipid. This increases the surface area, which increases the rate at which the lipid is broken down by the lipase.
  • Bile is alkaline, so it neutralises the stomach acid, creating alkaline conditions in the small intestine. This increases the rate of lipid digestion by lipase.
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3
Q

Explain why a person with a leaky heart valve has difficulty exercising.

A
  • Back-flow of blood can occur.
  • Less blood is pumped around the body.
  • Less oxygen is supplied to cells.
  • So less aerobic respiration happens.
  • So less energy is released.
  • So there is less efficient muscle contraction.
  • Anaerobic respiration takes place.
  • Lactic acid builds up.
  • This causes muscle fatigue.
  • Less removal of carbon dioxide from the blood.
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4
Q

Evaluate the uses of mechanical and biological heart valve replacements.

A

Mechanical Valves:
+ Longer lasting.
+ Survival rate at five years is higher.
+ Lower percentage of deaths due to heart-related problems.
- Blood clots on the brain are more likely after surgery.
- Anti-clotting medication must be taken for the rest of their life.
- Medication can lead to excessive bleeding after injury.
- Some patients say they can hear the valves opening and closing.

Biological Valves:
+ No additional medication is required.
- Ethical issues surrounding the use of animal tissue.
- Valve may harden.
- More likely to need another new valve.
- More likely to be rejected.
- More likely to need immuno-suppressant medication.

Both Valves:
+ Both are readily available.
+ Little wait time.

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5
Q

How are alveoli developed for gas exchange?

A
  • Large surface area to increase the rate of diffusion.
  • Thin walls for a short diffusion pathway.
  • Good blood supply to maintain a high concentration gradient.
  • Well ventilated to maintain a high concentration gradient.
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6
Q

How many types of tumours are there?

A

Two:
1) Benign.
2) Malignant.

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7
Q

Describe the two types of tumours.

A

Benign - Found in one area and does not spread to other parts of the body.
Malignant (Cancer) - Cells break off and invade other tissues, then travel through the bloodstream to form secondary tumours.

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8
Q

What are the risk factors for cancer?

A

Genetics:
- Breast, prostrate and large intestine cancer.

Lifestyle:
- Smoking: Lung Cancer.
- Ultraviolet Light: Skin Cancer.
- Alcohol: Mouth and throat cancer.

Substances in the Environment (Radon):
- Radon is a radioactive gas which increases the risk of developing lung cancer.
- Radon releases ionising radiation which damages DNA causing uncontrollable cell division.

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9
Q

What is the leaf?

A

An organ.

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10
Q

How many parts of the leaf and there and what are they?

A

1) Waxy cuticle layer.
2) Epidermis (upper and lower).
3) Palisade mesophyll.
4) Spongy mesophyll.
5) Pores called stomata.
6) Xylem tissue.
7) Phloem tissue.

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11
Q

What are the functions and adaptions of each part of the leaf?

A

1) Waxy cuticle layer:
- Thin layer of oily material.
- Reduces the evaporation of water or stops the leaf from drying out.

2) Epidermis:
- Protects the surface of the leaf.
- Transparent so it lets light pass through to the photosynthetic cells below.

3) Palisade mesophyll:
- Consists of palisade cells.
- Lost chloroplasts that contain chlorophyll for photosynthesis.

4) Spongy mesophyll:
- Full of air spaces to allow CO2 to diffuse to the palisade cells.
- Lots of chloroplasts that contain chlorophyll for photosynthesis.

5) Stomata:
- For gas exchange and control water vapour (water loss).
- Allow CO2 to come in and O2 to go out.

6) Xylem tissue:
- Transports dissolved mineral ions.
- Magnesium is used to make chloroplasts.
- Transports water from the roots to the stems and leaves.
- Some water is used in photosynthesis.

7) Phloem tissue:
- Transports dissolved sugars produced by photosynthesis from the leaves to the rest of the plant.
- This movement is called translocation.

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12
Q

What is digestion?

A

The process of nutrients being absorbed from food into the body.

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13
Q

What is an enzyme?

A
  • A large protein molecule.
  • A biological catalyst that doesn’t get used up.
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14
Q

Describe the ‘lock and key’ theory.

A
  • Enzymes are specific.
  • The substrate has to have a complimentary shape to the active site on the enzyme.
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15
Q

Name the 3 types of enzymes.

A
  • Amylase.
  • Protease.
  • Lipase.
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16
Q

Where is protease made and what does it break down?

A
  • Small intestine, pancreas and stomach.
  • Breaks down protein into amino acids.
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17
Q

Where is amylase made and what does it break down?

A
  • Small intestine, pancreas and salivary glands.
  • Breaks down starch into simple sugars such as glucose.
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18
Q

Where is lipase made and what does it break down?

A
  • Small intestine and pancreas.
  • Breaks down lipids into 1 glycerol and 3 fatty acids.
19
Q

What 2 factors affect enzyme activity?

A
  • pH.
  • Temperature.
20
Q

How does the temperature and pH affect enzyme activity?

A
  • There is an optimum pH and temperature (where the enzyme works best in).
  • After the pH/temperature rises above this, the enzymes active site becomes denatured.
  • This means it is no longer complimentary to the substrate so it cannot form an enzyme substate complex.
21
Q

How is the small intestine adapted for digestion?

A
  • It has millions of tiny projections called villi which increases surface area, increasing the rate of diffusion.
  • Villi have microvilli which further increase the surface, increasing the rate of diffusion.
  • One cell thick walls provide a short diffusion pathway, increasing the rate of diffusion.
  • Good blood supple to maintain a high concentration gradient, increasing the rate of diffusion.
22
Q

What is a single circulatory system?

A

When blood enters the heart once.

23
Q

What are the problems with a single circulatory system?

A

The blood loses it’s pressure as it continues so oxygen isn’t given to the cells.

24
Q

What is a double circulatory system?

A

When blood enters the heart twice.
- Blood enters into the right side of the heart and goes to the lungs.
- Blood enters the left side of the heart and goes all around the body.

25
Q

What is the benefit of a double circulatory system?

A

Blood will easily flow around the body.

26
Q

Why does the left ventricle have thicker muscle?

A

To assist it to pump blood all around the body.

27
Q

Where are coronary arteries found?

A

They branch out of the aorta and into the heart.

28
Q

What is the purpose of coronary arteries?

A

To supply oxygenated blood to the heart muscle cells for aerobic respiration to generate energy so the cells can contract and pump blood around the body.

29
Q

Where are pacemaker cells found?

A

Right atrium of the heart.

30
Q

What is the job of pacemaker cells?

A

To regulate the heartbeat.

31
Q

What is the job of an artificial pacemaker?

A

To send electrical impulses to regulate the heartbeat when the natural pacemaker cells don’t work.

32
Q

What condition do artificial pacemakers treat?

A

Irregular heartbeat.

33
Q

Name 3 blood vessels and their adaptations.

A

• Artery (carries blood at high pressure):
- Thick muscular walls to withstand high pressure.
- Elastic fibres that open the artery up to let blood flow. They then spring back into place.

• Vein (carries blood at low pressure):
- Valves prevent back flow of blood.
- Large lumen so more blood can flow.

• Capillary:
- Thin walls for a short diffusion pathway which increases the rate of diffusion.

34
Q

What 4 components make up blood?

A

1) Red blood cells.
2) White blood cells.
3) Platelets.
4) Plasma.

35
Q

Describe the functions of the 4 different parts of blood.

A

1) Red blood cells carry oxygen to organs. They have haemoglobin which is what oxygen binds to. They have a biconcave shape which increases surface area so more oxygen can bind to it and no nucleus so there is more space for oxygen to bind to.

2) White blood cells are apart of the immune system. They produce antibodies and antitoxins to fight off infections.

3) Platelets are involved in blood clotting.

4) Plasma carries red and white blood cells, platelets, nutrients such as glucose and amino acids, carbon dioxide, urea, hormones, proteins, antibodies and antitoxins.

36
Q

What are the pros and cons with donated blood?

A

+ Safe
+ Keep people alive even if they lose 2/3 of their red blood cells.
- Unsafe if air bubbles get in the blood.
- Don’t replace the function of red blood cells.

37
Q

What is transpiration?

A

Water is evaporated from the surface of the leaf. The water vapour diffuses through the air spaces in the spongy mesophyll and out of the leaf through the stomata. This is known as the transpiration stream. Water passes from the xylem into the lead to replace the water that has been lost.

38
Q

What are the 4 factors that affect transpiration?

A

1) High temperature - more heat means more evaporation.

2) Dry conditions.

3) Wind condition - wind removes water vapour.

4) Increased light intensity - more photosynthesis will occur so the stomata will open up for CO2 but water vapour will be lost.

39
Q

Describe the test for starch, protein, lipids, and sugar.

A

Starch - Use iodine as a reagent. Add a few drops of iodine. If there is a positive result, it will go from orange to blue/black.

Protein - Use Biuret’s solution as a reagent. Add a few drops of Biuret’s solution. If there is a positive result, it will go from blue to purple.

Lipids - Use Sudan III as a reagent. Add a few drops of Sudan III. If there is a positive result, a red layer will form on top.

Sugar - Use Benedict’s solution as a reagent. Add a few drops of Benedict’s solution and place it in a water bath at above 65 degrees C for 5 minutes. If there is a positive result, it will turn from blue to brick red.

40
Q

What are the adaptations of the small intestine?

A
  • Villi have microvilli which provide a large surface area, increasing the rate of absorption.
  • They are one cell thick, providing a short diffusion pathway.
  • Small intestine is very long, which increases the surface area.
  • Good blood supply to maintain concentration gradient.
  • Cells have lots of mitochondria for aerobic respiration to provide energy for active transport.
41
Q

What is a cardiovascular disease?

A

A disease of the heart and blood vessels.
It is non communicable.

42
Q

Describe coronary heart disease.

A
  • Layers of fatty material build up inside of the coronary arteries.
  • This causes the arteries to narrow.
  • This reduces the flow of oxygenated blood reaching the heart muscle cells, so less oxygenated blood reaches the heart muscle cells
  • This means less respiration happens and less energy is made.
  • This means that heart cannot contract efficiently.
  • This can reduce the amount of oxygenated blood pumped around the body.
  • In extreme cases, this can cause a heart attack.
43
Q

Evaluate the use of stents and statins.

A

Stents:
+ Blocked artery is held open
+ Blood flow to the heart muscle cells is increased
+ Stent will remain in place for a long time
+ Effect of stents are immediate
+ Rapid recovery from the operation
- Risk of infection from operation
- Risk of surgery such as a heart attack
- Risk of blood clots

Statins:
+ Easy to take
+ Decrease blood cholesterol
+ Slow down the build up of fatty materials in arteries
+ Maintain the blood flow to the heart muscle cells
+ Cheap compared to the stent operation
- Might be side effects of the drug
- Effects take time to happen
- Drug will need to be taken long term
- Might forget to take drug

44
Q

Evaluate the treatment for heart failure.

A

Treatment:
Patients are given a donated heart.

Problems:
- Not enough donated hearts for the number of patients.
- Patient needs to take drugs to stop the donated heart being rejected by the persons immune system

Solutions:
- Patients can be given an artificial heart as a temporary solution while waiting for a heart transplant.
- However, artificial hearts can increase the risk of blood clotting.