B11 - Hormonal Coordination Flashcards
What is ADH?
anti-diuretic hormone that helps control the water balance of the body and affects the amount of urine produced by the kidney
What is adrenaline?
Adrenaline is produced by the adrenal glands above the kidneys, it is a hormone that prepares the body for flight or fight
What is contraception?
Methods of preventing pregnancy which usually involves preventing sperm and egg from meeting
What is the endocrine system?
The endocrine system is made up of the glands that produce hormones that control many aspects of the development and metabolism of the body, and the hormones they produce
What is follicle stimulating hormone?
FSH is a hormone that causes the eggs to mature in the ovary
What is glucagon?
Hormone involved in the control of blood sugar levels
What are hormones?
Chemicals produced in one area of the body of an organism that have an effect on the functioning of another area of the body. In animals hormones are produced in glands
What is insulin?
hormone involved in the control of blood sugar levels
What is oestogen?
Female sex hormone that controls the development of secondary sexual characteristics in girls at puberty, and the build-up and maintenance of the uterus lining during the menstrual cycle
What are ovaries?
Female sex organs that produce eggs and sex hormones
What is ovulation?
The release of a mature egg (ovum) from the ovary
What is the pituitary gland?
Endocrine “master gland” found in the brain that secretes a number of different hormones into the blood in response to different conditions to control other endocrine glands in the body
What is testosterone?
The main male sex hormone that controls the male secondary sexual characteristics at puberty and the production of sperm
What is type 1 diabetes?
A disroder where the pancreas fails to produce sufficient insulin
What is type 2 diabetes?
A disorder where the body cells no longer responds to the insulin produced by the pancreas
What happens if a healthy person has low blood sugar levels?
The pancreas secretes glucagon which stimulates glycogen breakdown in the liver, converting it back to glucose. In tis way, the stored glucose is released back into the blood - raising the blood sugar levels
What happens if a healthy person has high blood sugar levels?
The pancreas secretes a hormone called insulin. Insulin stimulates the glucose uptake from the blood by cells, and the formation of glycogen from glucose. In this way, the blood sugar levels are lowered
Explain fully the role of FSH?
Follicle stimulating hormone is secreted by the pituitary gland. It makes eggs mature in their follicles in the ovaries. It also stimulates the ovaries to produce oestogen
Explain fully the role of Oestrogen:
Oestrogen is made and excreted by the ovaries in response to FSH. It stimulates the lining of the uterus to grow again after menstruation in preparation for pregnancy. High levels of oestrogen inhibit the production of more FSH and stimulate the release of LH
Explain fully the role of LH:
Luteinising hormone is secreted by the pituitary gland and stimulates the release of a mature egg from the ovary. Once ovulation has taken place, LH levels fall again. LH inhibits the production of more oestrogen and stimulates the production of progesterone
Explain fully the role of progesterone:
Progesterone is secreted by the empty egg follicle in the ovary after ovulation. It is one of the hormones that helps to maintain a pregnancy if the egg is fertilised. Progesterone inhibits both FSH and LH and it maintains the lining of the uterus in the second half of the cycle, so it is ready to receive a developing embryo if the egg is fertilised. If fertilisation does not happen, then progesterone levels fall and the uterus lining pulls away, causing a new cycle to begin
Why is the endocrine system needed if animals already have a nervous system?
The endocrine system helps long-term changes happen within the body over a longer period of time, over days or even years rather than second to second or minute to minute
Explain how the endocrine system works:
The endocrine system is made up of glands that secrete chemicals called hormones directly into the bloodstream. The blood carries the hormone to its target organ where it produces an effect. The target organ has receptors on the cell membranes that pick up the hormone molecules, triggering a response in the cell
What is the main role of hormones produced by the pituitary gland?
*Controls growth in children
*Stimulates the thyroid gland to made thyroxine to control the rate of metabolism
*Stimulates the sexual organs to produce hormones
What is the main role of hormones produced by the thyroid gland?
Controls the metabolic rate of the body
What is the main role of hormones produced by the pancreas?
Controls the levels of glucose in the blood
What is the main role of hormones produced by the adrenal gland?
Prepares the body for stressful situations - “fight or flight” response
What is the main role of hormones produced by the ovaries?
Controls the development of the female secondary sexual characteristics and is involved in the menstrual cycle
What is the main role of hormones produced by the testes?
Controls the development of the female secondary sexual characteristics and is involved in the production of sperm
Name 6 important endocrine glands:
*Pituitary gland
*Thyroid gland
*Pancreas
*Adrenal gland
*Ovaries
*Testes
Why is control of the blood glucose levels needed?
When you digest a meal, large amounts of glucose pass into your blood. Without a control mechanism, your blood glucose levels would vary significantly. They would range from very high straight after a meal, to very low several hours later - so low that the cells would not have enough glucose to respire. This situation is prevented by your pancreas. IT constantly monitors and controls your blood glucose concentration.
What happens if glucose is converted to glycogen but the liver and muscles are already at maximum glycogen capacity?
The excess glycogen is converted into lipids and stored. If you regularly take in food that results in having more glucose than the liver and muscles can store as glycogen, you will gradually store more and more of it as lipids and may eventually become obese
Explain what type 1 diabetes is:
If your pancreas does not make enough (or any) insulin, your blood glucose concentration is not controlled. This is called type 1 diabetes. Without insulin your blood glucose levels get very high after you eat. Eventually your kidneys excrete glucose in your urine. you produce lots of urine and feel thirsty all the time. Without insulin, glucose cannot get into the cells of your body, so you lack energy and feel tired. You break down fat and protein to use as fuel instead, so you lose weight. Type 1 diabetes is a disorder that usually starts in young children and teenagers. There also seems to be a genetic element to the development of the disease
Explain what type 2 diabetes is:
Type 2 diabetes gets more common as people get older and it is often linked to obesity, lack of exercise, or both. There is also a strong genetic tendency to develop type 2 diabetes. In type 2 diabetes, the pancreas still makes insulin, although it may make less than your body needs. More importantly, your body cells stop responding to the insulin you make. In countries such as the UK and USA, levels of type 2 diabetes are rising rapidly as obesity becomes more common
What would happen if diabetes is not treated?
The person would waste away and fall into a coma before dying
How do you treat type 1 diabetes?
If you have type 1 diabetes, you need replacement insulin before meals. Insulin is a protein that would be digested in your stomach, so it is usually given as an injection to get it into your blood. The insulin allows glucose to be taken into your body cells and converted to glycogen in the liver. This stops the concentration of glucose in your blood from getting too high. Then, as blood glucose levels fall, the glycogen is converted back to glucose. As a result, your blood glucose levels are kept as stable as possible.
If you have type 1 diabetes you must also be careful about the levels of carbohydrate that you eat. You need to have regular meals, and exercise to keep your heart and blood vessels healthy. However, taking exercise needs to be carefully planned to keep your blood glucose levels steady. Your cells need enough glucose to respire more rapidly to produce to energy required for your muscles to work
How can you cure type 1 diabetes?
*Doctors can perform a pancreas transplant, however the operations are difficult and risky. Only a few hundred pancreas transplants take place each year in the UK. There are also not enough pancreas donors available. In addition, the patient exchanges one medicine (insulin) for another (immunosuppressants)
*Transplanting the pancreatic cells that make insulin dead and living donors has been tried but with limited success
*Stem cells are also being used to attempt to create insulin-secreting cells
How can you treat type 2 diabetes?
Type 2 diabetes can be cured by restoring their normal blood glucose balance, this can be done by:
*Eating a balanced diet with controlled amount of carbohydrates
*Losing weight
*Doing regular exercise
If this doesn’t help there are drugs which can:
*Help insulin work better on the body cells
*Help your pancreas make more insulin
*Reduce the amount of glucose you absorb from your gut into your bloodstream
If this does not work you will need insulin injections
Explain how negative feedback works:
Negative feedback systems work to maintain a steady state. If a factor in the internal environment increases, changes take place to reduce it and restore the original level. If a factor in the internal environment decreases, changes take place to increase it and restore the original level. Whatever the initial change, in negative feedback the response causes the opposite. Many hormones are involved in negative feedback systems, including insulin and glucagon, most female sex hormones, and thyroxine
What happens in a negative feedback system if the level rises above the ideal level?
The receptors will detect the change and then the response lowers the level back to the ideal level
What happens in a negative feedback system if the level falls belowthe ideal level?
The receptors will detect the change and then the response rises the level back to the ideal level
What is thyroxine?
The thyroid gland in your neck uses iodine from your diet to produce the hormone thyroxine. This controls the basal metabolic rate of your body - how quickly substances are broken down and built up, how much oxygen is used by tissues, and how the brain of a growing child develops. Thyroxine plays an important tole in growth and development
How does the level of thyroxine rely on negative feedback?
In adults, the level of thyroxine usually remain stable. This happens as a result of a negative feedback control involving the pituitary gland and the hormone it produces - thyroid stimulating hormone (TSH). If the levels of thyroxine in the blood begin to fall, it is detected by the sensors in the brain. As a result, the amount of TSH released from the pituitary gland increases. This is a negative feedback system. TSH stimulates the production of thyroxine by the thyroid gland. As the level of thyroxine goes up, it is detected by the sensors and in turn the level of TSH released falls