B10 H+S Flashcards

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1
Q

What is sensitivity?

A

true positives, the proportion of positives that are correctly identified. “will it pick up everyone that has the disease”

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2
Q

sensitivity equation

A

sensitivity= true positives/ true positives and false negatives (how many are true based on all the people with)

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3
Q

what is specificity?

A

true negatives, measures the proportion of negatives that are correctly identified. “will it pick up only the people with the disease, thus leaving all the people without the disease”

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4
Q

specificity equation

A

specificity= true negatives/ true negatives+ false positives (how many are false based on all the people that are false)

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5
Q

what does true positive mean?

A

test indicates disease when there is a disease

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6
Q

what does true negative mean?

A

test indicates no disease when no disease

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7
Q

false positive?

A

says is disease when no disease

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8
Q

positive predictive value?

A

probability of subjects with positive screening having the disease

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9
Q

negative predictive value?

A

probability that subjects with a negative screening truly don’t have the disease

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10
Q

Sensitivity test useful when?

A

when the result is negative- sensitivity rule out or snout. (if sensitivity is high and you are negative, youre likely to be negative)

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11
Q

specificity test useful when?

A

if the test is positive you can be quite sure that they have the disease- sensitivity rule in or spin.

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12
Q

+ve predictive value calculation?

A

true positive/ true positive+ false positive

how many people of the positives actually have the disease.

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13
Q

what is likelihood ratio?

A

likelihood that given test resultwould be expected in a patient with target disorder, compared to likelihood that same reusult would be in patient without target disorder (if +ve result, how likely to have disease?)

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14
Q

things commonly screened for?

A
Cancers
PPD- TB
prenatal tests
ultrasound- AAA
diabetic checks
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15
Q

limitations of screening?

A

cost and use of medical resources
adverse screening effects
stress and anxiety caused by false positive

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16
Q

pros of good screening

A

early detection, reduced risk of death

17
Q

cons of good screening

A

some people get tests etc with no benefit, some may get ill despite it being negative.

18
Q

what is sojourn time?

A

duration of a disease before clinical symptoms are apparent but is still detectable by screening.

19
Q

what is length bias?

A

a form of selection bias, more likely to screen people with longer progressive diseases. Could show that screening lengthens life but its just cos longer sojourn time.

20
Q

consequences of lead time bias?

A

disease with longer sojourn time easier to catch. Will get distorted picture of screening and prognosis

21
Q

lead time bias?

A

the earlier you diagnose the disease through screening, longer the patient will appear to survive (same time regardless

22
Q

consequence of lead time bias

A

survival inevitably longer following diagnosis due to extra time. Measure of effectiveness is deaths prevented, not survival.

23
Q

pseudodisease meaning

A

subclinical disease that would not become overt before the patient dies of other causes

24
Q

things BPH is elevated in?

A

prostate cancer, BPH, UTI

25
Q

what is opportunity cost?

A

loss of alternatives when one is chosen.

26
Q

what is distributive justice?

A

distributing finite reousources fairly.

27
Q

Ways to distribute healthcare?

A

QALY, waiting list, compliance, lifestyle choices, ability to pay

28
Q

3 ways confidentiality may be breached

A

statute (law
consent by patient
publics best interests

29
Q

3 laws that oblige doctors to disclose info

A

public health act 1984
road traffic act 1988
prevention of terror 1989