B Lactam Drugs Flashcards

1
Q

What type of penicillin is aqueous Penicillin G?

A

Natural Penicillin

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2
Q

What type of penicillin is benzathine penicillin?

A

Natural Penicillin

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3
Q

What type of penicillin is procaine penicillin G?

A

Natural Penicillin

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4
Q

What type of penicillin is penicillin VK?

A

Natural Penicillin

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5
Q

What type of penicillin is Nafcillin?

A

Penicillinase-resistant

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6
Q

What type of penicillin is oxacillin?

A

Penicillinase-resistant

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7
Q

What type of penicillin is methicillin?

A

Penicillinase-Resistant

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8
Q

What type of penicillin is dicloxacillin?

A

Penicillinase-Resistant

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9
Q

What type of penicillin is ampicillin?

A

Aminopenicillin

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10
Q

What type of penicillin is amoxicillin?

A

Aminopenicillin

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11
Q

What type of penicillin is is ticaricillin?

A

Carboxypenicillins

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12
Q

What type of penicillin is piperacillin?

A

Ureidopenicillin

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13
Q

Ampicillin-sulbactam brand name?

A

Unasyn

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14
Q

Amoxicillin-clavulanate brand name?

A

Augmentin

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15
Q

Ticarcillin-clavuanate brand name?

A

Timentin

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16
Q

Piperacillin-tazobactam brand name?

A

Zosyn

17
Q

What is the B-lactam mechanism of action?

A

Inhibitors of cell wall synthesis

18
Q

What 3 mechanisms of resistance are involved with B-lactams?

A
  1. B-lactamase enzymes
  2. Alterations in PBPs
  3. Decreased permeability of the outer cell membrane in Gram (-) bacteria
19
Q

What pharmacodynamic properties are displayed by B-lactams?

A

Time dependent bactericidal activity

T>MIC

20
Q

Describe the half life of B lactic antibiotics

A

Short (<2 hours) for most

21
Q

How are B lactase usually eliminated?

A

Glomerular filtration

Tubular secretion

22
Q

What penicillin is not excreted by the kidneys?

A

Nafcillin - biliary secretion

23
Q

What B lactam does not have cross allergenicity?

A

aztreonam