Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

SFM II > B Cell Immunity > Flashcards

B Cell Immunity Flashcards

1
Q

What are the Co-BCR receptors?

A

CD19, CD81 and CR2/CD21

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Naive B cells entering lymph nodes express

A

L selectin, CXCR5 and LFA-1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the B cell adaptor protein?

A

Syk-B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

TfH secrete what cytokine for B cell survival

A

IL-21

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

IL-4 primary isotype switch

A

IgG1 and IgE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Il-5 primary isotype switch

A

IgA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

IFN-Y primary isotype switch

A

IgG2a and IgG3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

TGF-B primary isotype switch

A

IgG2b and IgA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

AID function

A

Involved in somatic hypermutation that converts Cs to Us

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

CD27

A

B plasma cell marker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Memory B cell markers

A

Cd27 and CD45

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Memory B cell anti-apoptotic protein

A

Bcl-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is unique about t independent b cell act?

A

No class switching, no affinity matu and little to no memory. IgM uses for short term antibody protection.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

B cell inhibitory receptor

A

FcyRIIB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

FcYRI also known as

A

CD64

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

FcYRI

A

(CD64) involved in phagocytosis and act. of phagocytes like macro, neutro and eosinoph.

17
Q

FcYRIIA and FcYRIIB also known as

A

CD32

18
Q

FcYRIIA

A

Less inefficient cell activation and phagocytosis. Act. macro, neuto, eosinop. and platelets.

19
Q

FcYRIIB

A

Involved in feedback inhibition of B cells and attentuation of inflamm. Act. B lymph, DCs, mast cells, neut. and macro.

20
Q

FcYRIIIA also known as

A

CD16

21
Q

FcYRIIIA

A

Involved in antibody dependent cellular cytoxicity(ADCC). Involves NK cells.

22
Q

FceRI

A

Activation or degranulation of mast and basophils. Involves mast, baso and eosin.

23
Q

FcRn

A

Neonatal, IgG specific. Maintain IgG levels and increases Half life of it too.

24
Q

FcRn on

A 
APCS
Neut
Vascular endothelium
Mucosal epithelial cells
Podocytes

SFM II (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions