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FA Pharm > Autonomics - general > Flashcards

Autonomics - general Flashcards

1
Q

Alpha1

A

Inc vascular sm contraction, Inc Pupillary dilator muscle constraction (mydriasis), Inc intestinal an bladder sphincter muscle contraction

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2
Q

Inc Vascular sm muscle contraction

A

Alpha1

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3
Q

Inc Pupillary dilator muscle constraction (mydriasis)

A

Alpha1

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4
Q

Inc intestinal an bladder sphincter muscle contraction

A

Alpha1

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5
Q

Alpha2

A

Dec sympathetic tone, Dec insulin release, Dec lipolysis, Inc Platelet Aggregation

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6
Q

Dec sympathetic outflow

A

Alpha2

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7
Q

Dec insulin release

A

Alpha2

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8
Q

Dec lipolysis

A

Alpha2

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9
Q

Inc platelet aggregation

A

Alpha2

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10
Q

Beta1

A

Inc HR, Inc contractility, Inc renin release, Inc lipolysis

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11
Q

Inc HR

A

Beta1

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12
Q

Inc contractility

A

Beta1

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13
Q

Inc renin release

A

Beta1

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14
Q

Inc lipolysis

A

Beta1

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15
Q

Beta2

A

Vasodilation, Bronchodilation, Inc HR, Inc contractility, Inc lipolysis, Inc insulin release, Dec uterine tone (tocolysis), Ciliary muscle relaxation, Inc aqueous humor production

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16
Q

Vasodilation

A

Beta2

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17
Q

Bronchodilation

A

Beta2

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18
Q

Inc HR

A

Beta2

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19
Q

Inc contractility

A

Beta2

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20
Q

Inc lipolysis

A

Beta2

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21
Q

Inc insulin release

A

Beta2

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22
Q

Dec uterine tone (tocolysis)

A

Beta2

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23
Q

Ciliary muscle relexation

A

Beta2

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24
Q

Inc aqueous humor production

A

Beta2

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25
Q

M1

A

CNS, enteric nervous system

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26
Q

M2

A

Dec HR and contractility of atriia

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27
Q

M3

A

Inc exocrine gland secretion (e.g. lacrimal, salivary, gastric acid), Inc gut peristalsis, Inc bladder contraction, bronchoconstriction, Inc papillary sphincter muscle contraction (miosis), ciliary muscle contraction (accommodation)

28
Q

Inc exocrine glands secretion(lacrimal, salivary, gastric)

A

M3

29
Q

Inc gut peristalsis

A

M3

30
Q

Inc Bladder contraction

A

M3

31
Q

Bronchoconstriction

A

M3

32
Q

Inc pupillary sphincter muscle contraction (miosis)

A

M3

33
Q

Cilirary m. contraction (accommodation)

A

M3

34
Q

D1

A

Relaxes renal vascular smooth m.

35
Q

Relaxes renal vascular smooth m.

A

D1

36
Q

D2

A

Modulates NT release, esp in brain

37
Q

Modulate NT release, esp in brain

A

D2

38
Q

H1

A

Inc nasal and bronchial mucus production, Inc vacular permeability, Contraction of bronchioles, pruritus, and pain

39
Q

Inc nasal and bronchial mucus production

A

H1

40
Q

Inc vascular permeability

A

H1

41
Q

Contraction of bronchioles

A

H1

42
Q

Pruritus

A

H1

43
Q

Pain

A

H1

44
Q

Inc gastric acid secretion

A

H2

45
Q

H2

A

Inc gastric acid secretion

46
Q

V1

A

Inc vascular smooth muscle contraction

47
Q

V2

A

Inc H2O permeability and resorption in the CT of kidney

48
Q

Alpha1

A

Gq

49
Q

Alpha2

A

Gi

50
Q

Beta1

A

Gs

51
Q

Beta2

A

Gs

52
Q

M1

A

Gq

53
Q

M2

A

Gi

54
Q

M3

A

Gq

55
Q

D1

A

Gs

56
Q

D2

A

Gi

57
Q

H1

A

Gq

58
Q

H2

A

Gs

59
Q

V1

A

Gq

60
Q

V2

A

Gs

61
Q

Gq pathway

A

PLC cleaves PIP2 -> DAG + IP3. DAG -> PKC. IP3 -> Calcium increase -> Smooth Muscle contraction

62
Q

Gq listing

A

Alpha1, M1, M3, H1, and V1

63
Q

Gs listing

A

Beta1, Beta2, D1, H2, V2

64
Q

Gi listing

A

M2, Alpha2, D2

65
Q

Gs pathway

A

activate AC, cAMP, PKA -> inc Ca + myosin light-chain kinase (smooth muscle)

66
Q

Gi pathway

A

inhibit AC, cAMP, PKA -> dec Ca2+

FA Pharm (11 decks)

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