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REVIEW > Autonomic-Nervous-system-Drugs-studenT > Flashcards

Autonomic-Nervous-system-Drugs-studenT Flashcards

1
Q

often referred to as the “fight-or-flight” system

A

Sympathetic Nervous System

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2
Q

Primarily on smooth muscle cells, particularly in
blood vessels, iris dilator muscle, bladder sphincter, and salivary glands

A

Alpha 1

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3
Q
  • Primarily on presynaptic nerve terminals and act as a modulator of NE release
A

Alpha 2

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4
Q

Primarily located in the heart

A

Beta 1

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5
Q

Primarily located in the lungs, smooth muscles of the blood vessels and uterine muscles

A

Beta 2

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6
Q
  • Primarily located in adipose tissue
A

Beta 3

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7
Q

SYMPATHETIC NERVOUS SYSTEM is Responsible for preparing the body to ____________________.

A

respond to stress

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8
Q

Drugs that mimic the effect of the norepinephrine(2 answer)

A
  1. Sympathomimetics
  2. Adrenergic agonists
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9
Q

Drug that blocks the effect of norepinephrine
(2 answer)

A
  1. Sympatholytics
  2. Adrenergic Antagonist
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10
Q

Also termed as cholinergic/ craniosacral system

A

PARASYMPATHETIC NERVOUS SYSTEM

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11
Q

____________ is the major neurotransmitter.

A

Acetylcholine

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12
Q

Drugs that mimic acetylcholine(2 answer)

A
  1. Parasympathomimetics
  2. Cholinergic agonists
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13
Q

Drugs that block acetylcholine(2 answer)

A
  1. Parasympatholytics
  2. Cholinergic antagonists
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14
Q
  • Used in emergencies
  • Treats Allergic reaction, anaphylaxis,bronchospasm & cardiac arrest
  • Potent inotropic drug
A

Epinephrine

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15
Q
  • Potent vasoconstrictor that increases BP and cardiac output
A

Norepinephrine

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16
Q
  • Selective for beta-2 adrenergic receptors
  • Response: bronchodilation
  • Used to treat bronchospasm, asthma: bronchitis
  • Should not be given with MAOI (can cause hypertensive crisis)
A

Albuterol

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17
Q
  • Acts on B1 & B2 receptors
  • Response: Bronchodilation
A

Isoproterenol

18
Q
  • Used to treat hypotensive state, bronchospasm
  • Relief of hay fever, sinusitis and allergic rhinitis
A

Ephedrine

19
Q
  • Selective Alpha 2 adrenergic drug
  • used to treat hypertension
A

Clonidine

20
Q
  • Drug of choice for shock
A

Dopamine

21
Q
  • Used in treatment of CHF as it increases contractility without change in rate or increase in O2 demand.
A

Dobutamine

22
Q

antidote for NE and dopamine overdose.

A

Phentolamine

23
Q
  • Drugs that block or inhibit a response at the alphaadrenergic receptor sites
A

Alpha-adrenergic Blockers

24
Q

Non-selective Alpha Blockers (A1, A2 )

A

Phentolamine

25
Q

Selective Alpha Blockers (A1) (2 answer)

A
  • Doxazosin
  • Prazosin
26
Q

Non-selective Beta-adrenergic Blockers (B1, B2) (4 answer)

A
  • Propranolol
  • Carvedilol
  • Nadolol
  • Timolol
27
Q

Caution when giving Non-selective Beta-Adrenergic
Blockers: (3)

A
  • COPD
  • Bronchial Asthma
  • Diabetes Mellitus
28
Q

Selective Beta-1 Blockers (4)

A
  • Metoprolol
  • Atenolol
  • Acebutolol
  • Betaxolol
29
Q

Drugs that stimulate the parasympathetic nervous system.

A

CHOLINERGIC AGONISTS

30
Q

2 Types of Cholinergic Receptors

A
  • Muscarinic Receptors
  • Nicotinic Receptors
31
Q

Stimulate smooth muscles & slows heart rate.

A
  • Muscarinic Receptors
32
Q

Used to treat urinary retention and abdominal distention

A

Bethanechol (Urecholine)

33
Q
  • Constricts the pupil of the eye
  • Treatment of glaucoma
A

Pilocarpine

34
Q

SIGNS OF OVERDOSE (3)

A
  1. Salivations
  2. Sweating
  3. Abdominal cramps
35
Q

antidote for cholinergic overdose

A

ATROPINE SULFATE:

36
Q
  • Reversible Anti-cholinesterase (3)
A
  • Physostigmine
  • Neostigmine
  • Pyridostigmine
37
Q
  • Irreversible Cholinesterase (2)
A

-Potent agents
- Has long-lasting effect

38
Q

= antidote for irreversible acetylcholinesterase-inhibiting drugs

A

PRALIDOXIME

39
Q

“SLUDGE”

A

S - alivation
L - acrimation
U - rinary incontinence
D - iarrhea
G - astrointestinal cramps
E – mesis

40
Q
  • Drugs that inhibit the action Of acetylcholine by occupying Its receptors.
A

ANTI-CHOUNERGICS

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