Autonomic-Nervous-system-Drugs-studenT

Question 1

often referred to as the “fight-or-flight” system

Answer 1

Sympathetic Nervous System

Question 2

Primarily on smooth muscle cells, particularly in
blood vessels, iris dilator muscle, bladder sphincter, and salivary glands

Answer 2

Alpha 1

Question 3

• Primarily on presynaptic nerve terminals and act as a modulator of NE release

Answer 3

Alpha 2

Question 4

Primarily located in the heart

Answer 4

Beta 1

Question 5

Primarily located in the lungs, smooth muscles of the blood vessels and uterine muscles

Answer 5

Beta 2

Question 6

• Primarily located in adipose tissue

Answer 6

Beta 3

Question 7

SYMPATHETIC NERVOUS SYSTEM is Responsible for preparing the body to ____________________.

Answer 7

respond to stress

Question 8

Drugs that mimic the effect of the norepinephrine(2 answer)

Answer 8

1. Sympathomimetics
2. Adrenergic agonists

Question 9

Drug that blocks the effect of norepinephrine
(2 answer)

Answer 9

1. Sympatholytics
2. Adrenergic Antagonist

Question 10

Also termed as cholinergic/ craniosacral system

Answer 10

PARASYMPATHETIC NERVOUS SYSTEM

Question 11

____________ is the major neurotransmitter.

Answer 11

Acetylcholine

Question 12

Drugs that mimic acetylcholine(2 answer)

Answer 12

1. Parasympathomimetics
2. Cholinergic agonists

Question 13

Drugs that block acetylcholine(2 answer)

Answer 13

1. Parasympatholytics
2. Cholinergic antagonists

Question 14

• Used in emergencies
• Treats Allergic reaction, anaphylaxis,bronchospasm & cardiac arrest
• Potent inotropic drug

Answer 14

Epinephrine

Question 15

• Potent vasoconstrictor that increases BP and cardiac output

Answer 15

Norepinephrine

Question 16

• Selective for beta-2 adrenergic receptors
• Response: bronchodilation
• Used to treat bronchospasm, asthma: bronchitis
• Should not be given with MAOI (can cause hypertensive crisis)

Answer 16

Albuterol

Question 17

• Acts on B1 & B2 receptors
• Response: Bronchodilation

Answer 17

Isoproterenol

Question 18

• Used to treat hypotensive state, bronchospasm
• Relief of hay fever, sinusitis and allergic rhinitis

Answer 18

Ephedrine

Question 19

• Selective Alpha 2 adrenergic drug
• used to treat hypertension

Answer 19

Clonidine

Question 20

• Drug of choice for shock

Answer 20

Dopamine

Question 21

• Used in treatment of CHF as it increases contractility without change in rate or increase in O2 demand.

Answer 21

Dobutamine

Question 22

antidote for NE and dopamine overdose.

Answer 22

Phentolamine

Question 23

• Drugs that block or inhibit a response at the alphaadrenergic receptor sites

Answer 23

Alpha-adrenergic Blockers

Question 24

Non-selective Alpha Blockers (A1, A2 )

Answer 24

Phentolamine

Question 25

Selective Alpha Blockers (A1) (2 answer)

Answer 25

* Doxazosin * Prazosin

Question 26

Non-selective Beta-adrenergic Blockers (B1, B2) (4 answer)

Answer 26

* Propranolol * Carvedilol * Nadolol * Timolol

Question 27

Caution when giving Non-selective Beta-Adrenergic Blockers: (3)

Answer 27

* COPD * Bronchial Asthma * Diabetes Mellitus

Question 28

Selective Beta-1 Blockers (4)

Answer 28

* Metoprolol * Atenolol * Acebutolol * Betaxolol

Question 29

Drugs that stimulate the parasympathetic nervous system.

Answer 29

CHOLINERGIC AGONISTS

Question 30

2 Types of Cholinergic Receptors

Answer 30

* Muscarinic Receptors * Nicotinic Receptors

Question 31

Stimulate smooth muscles & slows heart rate.

Answer 31

* Muscarinic Receptors

Question 32

Used to treat urinary retention and abdominal distention

Answer 32

Bethanechol (Urecholine)

Question 33

- Constricts the pupil of the eye - Treatment of glaucoma

Answer 33

Pilocarpine

Question 34

SIGNS OF OVERDOSE (3)

Answer 34

1. Salivations 2. Sweating 3. Abdominal cramps

Question 35

antidote for cholinergic overdose

Answer 35

ATROPINE SULFATE:

Question 36

* Reversible Anti-cholinesterase (3)

Answer 36

- Physostigmine - Neostigmine - Pyridostigmine

Question 37

* Irreversible Cholinesterase (2)

Answer 37

-Potent agents - Has long-lasting effect

Question 38

= antidote for irreversible acetylcholinesterase-inhibiting drugs

Answer 38

PRALIDOXIME

Question 39

"SLUDGE"

Answer 39

S - alivation L - acrimation U - rinary incontinence D - iarrhea G - astrointestinal cramps E – mesis

Question 40

- Drugs that inhibit the action Of acetylcholine by occupying Its receptors.

Answer 40

ANTI-CHOUNERGICS