Autonomic Nervous System drugs

Question 1

What are the two branches of the ANS?

Answer 1

-SNS
- Parasympathetic nervous system

Question 2

Adrenergic agonists, also called ______, are drugs that mimic the effects of the SNS and are used to simulate the adrenergic receptor within the SNS.

Answer 2

SYMPATHOMIMETICS

Question 3

______ is used to treat shock, cardiac standstill, and certain arrhythmias when used systemically.

Answer 3

ISOPROTERENOL

Question 4

________ is an autoimmune disease characterized by antibodies to the ACh receptors.

Answer 4

MYASTHENIA

Question 5

These drugs block the effects of acetylcholine at cholinergic receptor sites, thus blocking the effects of the parasympathetic nervous system.

Answer 5

ANTICHOLINERGIC DRUGS

Question 6

_______ is made from choline and acetyl CoA

Answer 6

Acetycholine (ACh)

Question 7

ADVERSE REACTION :
DUMBBELS

Answer 7

D- Diarrhea
U- Urination
M- Miosis and Muscle Weakness
B- Bronchorrhea
B- Brachycardia
E- Emesis
L- Lacrimation
S- Salivation/Seating

Question 8

Parasympathetic nervous system blockage causes:

Answer 8

Increase in heart rate, decrease in GI activity, decrease in urinary bladder tone and function, pupil dilation and cycloplegia.

Question 9

What is the most commonly used anticholinergic drug that is indicated for a wide variety of conditions and is available in oral, parenteral, and topical forms?

Answer 9

Atropine

Question 10

______ are chemicals that act at the same site as the neurotransmitter ACh, stimulating the parasympathetic nerves, some nerves in the brain, and the neuromuscular junction.

Answer 10

Cholinergic drugs

Question 11

The patient is diagnosed with Alzheimer’s disease which is progressive dementia defined by neocortical loss of ACh-producing neurons and ACh receptor sites. To manage Alzheimer’s disease the ACh levels in the brain should be increasing and to slow the progression of the disease. what kind of inhibitor is used?

Answer 11

Acetylcholinesterase inhibitors

Question 12

Drugs act through receptors by binding to the receptors to initiate a response or prevent a response.

Answer 12

Receptor Theory

Question 13

________ drugs that produce a response that enhanced cellular activity

Answer 13

Agonist

Question 14

What is the goal of autonomic drugs?

Answer 14

-to correct disorders of target organs through autonomic nerves,

Question 15

List of effects of Alpha2-receptor

Answer 15

Blood vessels
- decreased blood pressure (reduced norepinephrine)
Smooth muscle (gastrointestinal tract)
- decreased gastrointestinal tone and motility

Question 16

Isoproterenol receptor and therapeutic use:

Answer 16

B1, B2
- to increase heart rate, force of contraction, and conduction.

Question 17

What are the side effects of adrenergic agonists? Give 3 side effects.

Answer 17

Tissue necrosis
Tachycardia, palpitation, tremors, dizziness, increased blood pressure
Urinary retention r/t high doses
Nausea and vomiting

Question 18

caused by an overdose of cholinergic agonists.

Answer 18

Cholinergic crisis

Question 19

ADVERSE EFFECT:
ABCDS

Answer 19

A- Agitation
B- Blurred vision
C- Constipation, Confusion
D- Dry mouth
S- Stasis of urine and sweating

Question 20

Nicotinic has 2 receptors that affect skeletal muscles. what are the 2 receptors?

Answer 20

Nm- muscle contraction
Nn- transmission of cholinergic signals