Autonomic Nervous System Drugs Flashcards
What are the two branches of the nervous system?
Central and Peripheral
Central nervous system is made up of…
Brain and spinal cord
Peripheral nervous system is made up of…
Afferent and Efferent
Autonomic nervous system is made up of…
Sympathetic and Parasympathetic
These neurons send impulses to the central nervous system
Afferent (Sensory)
These neurons receives impulses, transmit through spinal cord to effector organ cells
Efferent (Motor)
What are the difference between autonomic and somatic nervous system?
Autonomic NS
- Involuntary
- Controls and regulates the heart, GI,
respiratory system, bladder, eyes and
glands
Somatic NS
- Voluntary
- Innervates the skeletal muscles
Dilates pupils, dilates bronchioles, increases heart rate, constricts blood vessels, relaxes smooth muscles of the GI, relaxes uterine muscles
Sympathetic NS
Constricts pupils, constricts bronchioles, decreases heart rate, dilates blood vessels, increases peristalsis, increases salivation
Parasympathetic NS
- Drugs act through receptors by binding to the receptors to initiate a response or prevent a response
- It is similar to the fit of the right key in a lock
Receptor Theory
Parasympathetic NS’s terminal neurotransmitter
Acetylcholine
What is acetylcholinesterease?
Enzyme that inactivates acetylcholine before reaching organ
cells
What is the difference between agonist and antagonist?
Agonist - drugs that produce a response
Antagonist - drugs that block a response
Adrenergic antagonist vs. Adrenergic agonist
Adrenergic agonist
- Stimulate the SNS
- Sympathomimetic
Adrenergic antagonist
- Inhibit the SNS
- Sympatholytic
Catecholamines vs. Noncatecholamines
Catecholamine has a catechol ring and amines
Noncatecholamine has no catechol ring
