Autonomic Nervous System Drugs

Question 1

Drugs that affect the Autonomic Nervous System

Answer 1

Adrenergic Agonist
Adrenrgic Antagonist
Cholinergic Agonist
Cholinergic Antagonist

Question 2

An Effect when Autonomic drugs are given, the goal is not to treat an autonomic disorder, it is to correct disorders of target organs through autonomic nerves.

Answer 2

Pharmacologic Effect

Question 3

A type of ANS drug that stimulates adrenergic receptor

Answer 3

Sympathomimetics/ Adrenergic Agonist

Question 4

3 Mechanism of Action of Adrenergic Agonists

Answer 4

Direct-acting sympathomimetic
Indirect-acting sympathomimetic
Mixed-acting sympathomimetic

Question 5

Alpha 1 and Alpa 2 Receptors Treats what?

Answer 5

Alpha 1- Hypotension, Nasal congestion, dilation of pupils
Alpha 2- Hypertension

Question 6

Beta 1 and Beta 2 Receptors Treats what

Answer 6

Beta 1- Heart Failure, cardiac arrest, shock
Beta 2- Asthma, premature labors of contraction

Question 7

Adrenergenic Receptors of EPINEPHRINE and Its Therapeutic Use

Answer 7

Receptors: A1, A2, B1, B2
Therapeutic Use: Cardiac Arrest; asthma

Question 8

Adrenergenic Receptors of PSEUDOEPHEDRINE; PHENYELPHRINE and Its Therapeutic Use

Answer 8

Receptoers: A1, B2
Therapeutic Use: Nasal decongestant

Question 9

Adrenergic Receptor of ISOPROTERENOL and Its Therapeutic Use

Answer 9

Receptors: B1, B2
Therapeutic Use: Increase heart rate, force of contraction and conduction

Question 10

Adrenergenic Receptor of DOBUTAMINE and Its Therapeutic Use

Answer 10

Receptor: B1
Therapeutic Use: Increases heart rate, force of contraction in heart failure, shock

Question 11

Adrenergenic Receptor of ALBUTEROL and Its Therapeutic Use

Answer 11

Receptors: B2
Therapeutic Use: Asthma/ COPD

Question 12

A type of ANS drug that Blocks alpha and beta receptor blockers

Answer 12

Adrenergic Antagonists

Question 13

Adrenergic Antagonists Mechanism

Answer 13

• Direct Blocking by occupying receptors
• Indirect Blocking by inhibiting release of neurotransmitters

Question 14

Give atleast 1 Adrenergenic Antagonist Drug that have A1 or A2 Receptor and Its therapeutic use

Answer 14

Phentolamine, Phenoxybenzamine (A1, A2), Hypertension

Prazosin, Terazosin (A1), Hypertension

Tamsulosin, Alfuzosin (A1), BPH- Urinary Relief

Question 15

Give atleat 2 Adrenergenic Antagonist Drug that have B1 or B2 Receptor and Its Therapeutic use

Answer 15

Propanolol(1stgen) (B1,B2), Hypertension, Angina, Migraine

Timolol (1stgen) (B1,B2), Glaucoma, decrease intraocular pressure

Atenolol, Metoprolo (B1), Hypertension (2nd Gen- cardioselective)

Carvedilol, Labetalol (B1,B2), Hypertension- with Vasodilation

Pindolol (B1,B2), Decrease CO, HR for patients with heart block

Question 16

A type of Drug that mimic the parasympathetic neurotransmitter acetylcholin

Answer 16

Cholinergic Agonist

Question 17

Give 3 Direct and Indirect(Reversible) Acting Choligernic Agonists Drug

Answer 17

Direct Acting
- Acetylcholine
- Carbachol
- Pilocarpine
- Bethanechol

Indirect Acting
- Edrophonium
- Physostigmine
- Neostigmine
- Pyridostigmine
- Donepezil, Rivastigmine, Galantamne

Question 18

Agents that bind Cholinoreceptors (muscarinic and nicotinic)

Answer 18

Cholinergic Antagonists

Question 19

Give atleast 3 Anti-Muscalinic Agents

Answer 19

Atropine
Cyclopentolate, Tropicamide
Scopolamine
Ipratropium
Oxybutynin
Benztropine

Question 20

Depolarizing Agent that causes sodium channels to open for prolonged depolarization

Answer 20

Succinylcholine