Autonomic Drugs

Question 1

Cholinomimetic drugs picture

Answer 1

port town with mime drinking cola

Question 2

nicotinic receptors are where?

receptor does what, inercellularly

Answer 2

guy smoking leaning against pole and by outlet = autonomic ganglia
outlet = NMJ
wearing a hat = adrenals

it’s an ion channel = news channel on TV

Question 3

M1, M2, M3
intracellular mech
where are they located

Answer 3

QIQ mart
M1 - Gq, M2 - Gi, M3 - Gq
M1 - enteric and CNS = brain helmet

M2 - Heart = shirt shows atria, decreases conduction

M3 - smooth muscle and glands = paint on motorcycle
increasing smooth muscle –> NO –> dilation. If athrosclerosis - opposite effect = exhaust pipe

Question 4

4 cholinomimetics

Answer 4

Bethanechol - lady
Pilocarpine - pile of carp
Carbachol - guy in window (upper left)
Methacholine - race

Question 5

Bethanachol use

Answer 5

bowel and bladder = hoses

(doesn’t help with blockage

Question 6

Pilocarpine use

Answer 6

carp have wet mouths - saliva production - sjogrens

glaucoma - contraction of cilliary body –> lens relaxes, becomes more spherical = net is tight and has glass sp heres
guy with tight hood = pupillary constriction - helpful for closed angle glaucoma

Question 7

Carbachol use

Answer 7

guy above window because muscarine and nicotinic

hood is also tight = pupillary constriction = closed angle glaucoma

Question 8

methacholine use

Answer 8

marathon challenge = causes asthma durring testing

Question 9

smoking cessation drug

Answer 9

varenicline

poster behind guy says VERY CLEAN