Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Step 1 > Autonomic Drugs > Flashcards

Autonomic Drugs Flashcards

1
Q

Bethanechol

A
  • Direct cholinergic agonist
  • Activates bowel and bladder smooth muscle
  • Resistant to AChE
  • “Bethany, call me to activate your Bowels and Bladder”
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Carbachol

A
  • Direct cholinergic agonist
  • Consticts pupil and relieves intraocular pressure in glaucoma
    “Carbon copy of acetylcholine”
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Methacholine

A
  • Direct cholinergic agonist
  • Asthma challenge test
  • Stimulates muscarinic receptors in airway (M3)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Pilocarpine

A
  • Direct cholinergic agonist
  • Contracts ciliary muscle eye (open-angle glaucoma)
  • Contracts pupillary sphincter (closed-angle glaucoma)
  • Resistant to AChE
  • Potent stimulator of sweat, tears, saliva (“you cry, sweat, and drool on your PILow”)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Donepezil, galantamine, rivastigmine

A
  • Anticholinesterase

- Alzheimer Disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Edrophonium

A
  • Anticholinesterase

- Used to be used for diagnosis of myasthenia gravis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Neostigmine

A
  • Anticholinesterase
  • Postop and neurogenic ileus/urinary retention
  • Postop reversal of neuromuscular junction blockade
  • Myasthenia gravis
  • No CNS penetration
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Physostigmine

A
  • Anticholinesterase
  • Atropine overdose/anticholinergic toxicity
  • Penetrates CNS
  • “PHYxes atropine overdose”
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Pyridostigmine

A
  • Anticholinesterase
  • Myasthenia gravis
  • No CNS penetration
  • “PyRIDostiGMine gets RID of Myasthenia Gravis”
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Atropine, homatropine, tropicamide

A
  • Muscarinic antagonist
  • Mydriasis
  • Treat bradycardia
  • For atropine: caution in elderly due to acute angle-closure glaucoma, hyperthermia in infants, urinary retention in men with big prostates
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Benztropine

A
  • Muscarinic antagonist
  • Parkinson disease (CNS penetration)
  • “Park my Benz”
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Glycopyrrolate

A
  • Muscarinic antagonist
  • Oral: drooling, peptic ulcer
  • IV: preop reduction in airway secretions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Hyosycamine, dicyclomine

A
  • Muscarinic antagonist

- Antispasmodics for IBS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Ipratropium, tiotrupium

A
  • Muscarinic antagonist

- COPD and asthma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Oxybutynin, solifenacin, tolterodine

A
  • Muscarinic antagonist

- Reduce bladder spasms and urge urinary incontinence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Scopolamine

A
  • Muscarinic antagonist

- CNS penetration: motion sickness

17
Q

Albuterol

A
  • β2 > β1 agonist

- Acute asthma

18
Q

Salmeterol

A
  • β2 > β1 agonist

- Long-term asthma or COPD control

19
Q

Dobutamine

A
  • β1 > β2, α agonist
  • Heart failure (inotropic/chronotropic)
  • Cardiac stress testing
20
Q

Dopamine

A
  • D1 = D2 > β > α agonist
  • Unstable bradychardia, HF, shock
  • Inotropic and chronotorpic α effects predominate at high doses
21
Q

Epinephrine

A
  • β > α agonist
  • Anaphylaxis, asthma, open-angle glaucoma
  • α effects predominate at high doses
  • Way stronger at β2 receptor than norepinephrine
22
Q

Isoproterenol

A
  • β1 = β2 agonist
  • Used for electrophysiologic evaluation of tachyarrhtmias
  • Can worsen ischemia
  • Can increase contraction and decrease vascular resistance simultaneously
23
Q

Norepinephrine

A
  • α1 > α2 > β1 agonist
  • Treat hypotension (but will decrease renal perfusion)
  • NO β2
24
Q

Phenylephrine

A
  • α1 > α2 agonist

- Treat hypotension, rhinitis, and use for ocular procedures

25
Q

Clonidine

A
  • α2 agonist
  • Hypertensive urgency (does not decrease renal perfusion)
  • ADHD, Tourette syndrome
26
Q

α-methyldopa

A
  • α2 agonist
  • Hypertension in pregnancy
  • Can cause Direct Coombs + hemolysis and SLE-like syndrome
27
Q

Phenoxybenzamine

A
  • α blocker, non selective, irreversible

- Pheochromocytoma preoperatively

28
Q

Phentolamine

A
  • α blocker, non selective, reversible

- Give to pt on MAOI who eats tryamine-containing food

29
Q

Prazosin, terazosin, doxazosin, tamsulosin (-osin ending)

A
  • α1 blocker, selective

- PBH, PTSD (Prazosin), hypertension (except tamsulosin)

30
Q

Mirtazapine

A
  • α2 blocker, selective

- Depression

Step 1 (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions