Autoimmunity

Question 1

Loss of AIRE function leads to compromised _____ Selection in the Thymus

Answer 1

Negative

Question 2

Immune Dysregulation Polyendocrinopathy Eteropathy X-linked (IPEX) happens with a mutation in _____ gene, where children die within the first 2 years of life.

Answer 2

FOXP3

Question 3

_____ Proteins can explain why environmental factors such as smoking can modify “Self” and cause autoimmunity

Answer 3

Citrullinated