Autoimmune disease markers Flashcards

1
Q

Anti-Desmoglein Ab (IgG)

A

Pemphigus Vulgaris

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2
Q

Anti-SSa, Anti-SSb

A

Sjogrens (SS= Sjogrens syndrome)

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3
Q

Anti-SCL-70, Anti-Topoisomerase 1

A

Diffuse Scleroderma

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4
Q

Anti-GQ1b

A

Miller-Fisher Syndrome

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5
Q

Anti-GM1

A

Multifocal motor neuropathy

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6
Q

Anti-Jo1

A

Polymyositis/Dermatomyositis

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7
Q

Anti-Histone

A

Drug-Induced Lupus

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8
Q

Anti-GBM

A

Goodpastures syndrome

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9
Q

c-ANCA (PR3-ANCA)

A

Granulomatosis with polyangiitis (Wegeners)

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10
Q

p-ANCA (MPO-ANCA)

A

Microscopic polyangiitis

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11
Q

anti-CCP

A

Rheumatoid Arthritis

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12
Q

Anti-endomysial, Anti-TTG

A

Celiac Disease

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13
Q

Anticentromere

A

CREST (Limited Scleroderma)

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14
Q

Anti-Ro, Anti-La

A

Sjogren Syndrome

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15
Q

What antibodies cross the placenta and cause fetal conduction defects?

A

Anti-Ro (Seen in SLE and Sjogren)

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16
Q

Anti-Beta2GPI

A

Antiphospholipid syndrome (SLE)

17
Q

Anti-Smith, anti-dsDNA

A

SLE

18
Q

RNA-Pol 1 and 3

A

Diffuse Scleroderma

19
Q

Hypergammaglobulinemia

A

Sjogren Syndrome

20
Q

Anti-cN1A

A

Inclusion body myositis

21
Q

Anti-Mi2, anti-MDA5

A

Dermatomyositis