Autoimmune disease markers

Question 1

Anti-Desmoglein Ab (IgG)

Answer 1

Pemphigus Vulgaris

Question 2

Anti-SSa, Anti-SSb

Answer 2

Sjogrens (SS= Sjogrens syndrome)

Question 3

Anti-SCL-70, Anti-Topoisomerase 1

Answer 3

Diffuse Scleroderma

Question 4

Anti-GQ1b

Answer 4

Miller-Fisher Syndrome

Question 5

Anti-GM1

Answer 5

Multifocal motor neuropathy

Question 6

Anti-Jo1

Answer 6

Polymyositis/Dermatomyositis

Question 7

Anti-Histone

Answer 7

Drug-Induced Lupus

Question 8

Anti-GBM

Answer 8

Goodpastures syndrome

Question 9

c-ANCA (PR3-ANCA)

Answer 9

Granulomatosis with polyangiitis (Wegeners)

Question 10

p-ANCA (MPO-ANCA)

Answer 10

Microscopic polyangiitis

Question 11

anti-CCP

Answer 11

Rheumatoid Arthritis

Question 12

Anti-endomysial, Anti-TTG

Answer 12

Celiac Disease

Question 13

Anticentromere

Answer 13

CREST (Limited Scleroderma)

Question 14

Anti-Ro, Anti-La

Answer 14

Sjogren Syndrome

Question 15

What antibodies cross the placenta and cause fetal conduction defects?

Answer 15

Anti-Ro (Seen in SLE and Sjogren)

Question 16

Anti-Beta2GPI

Answer 16

Antiphospholipid syndrome (SLE)

Question 17

Anti-Smith, anti-dsDNA

Answer 17

SLE

Question 18

RNA-Pol 1 and 3

Answer 18

Diffuse Scleroderma

Question 19

Hypergammaglobulinemia

Answer 19

Sjogren Syndrome

Question 20

Anti-cN1A

Answer 20

Inclusion body myositis

Question 21

Anti-Mi2, anti-MDA5

Answer 21

Dermatomyositis