Autoantibody associations Flashcards

1
Q

Anti-AChR

A

Myasthenia gravis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Anti-basement membrane

A

Goodpasture syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Anticardiolipin

A

SLE, antiphospholipid syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Anticentromere

A

Limited scleroderma (CREST syndrome = Calcinosis, Raynaud’s, Esophageal dysmotility, Sclerodactyly, Telangiectasias)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Anti-desmosome

A

Pemphigus vulgaris

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Antihemidesmosome

A

Bullous pemphigoid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Anti-dsDNA, anti-Smith

A

SLE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Anti-glutamic acid decarboxylase

A

T1DM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Anti-histone

A

Drug-induced SLE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Anti-Jo-1, anti-SRP, anti-Mi-2

A

Polymyositis, dermatomyositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Antimicrosomal

A

Hashimoto thyroiditis

Also antithyroglobulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Antimitochondrial

A

Primary biliary cirrhosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Antinuclear

A

Nonspecific

SLE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Antiparietal cell

A

Pernicious anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Anti-Scl-70

A

AKA anti-DNA topoisomerase I

Diffuse scleroderma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Anti-smooth muscle

A

Autoimmune hepatitis

17
Q

Anti-SSA, Anti-SSB

A

Sjogren syndrome

18
Q

Anti-TSH receptor

A

Graves disease

19
Q

Anti-U1 RNP

A

Mixed Connective Tissue Disease

20
Q

IgA anti-endomysial, IgA anti-tissue transglutaminase

A

Celiac disease

21
Q

p-ANCA

A

AKA MPO-ANCA

Microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)

22
Q

c-ANCA

A

AKA PR3-ANCA

Granulomatosis with polyangiitis (Wegener’s)

23
Q

IgM targetting IgG Fc region

A

AKA RF
RA
RF is not as specific as anti-CCP