Autoantibodies Flashcards

1
Q

Anti-ACh Receptor

A

Myasthenia Gravis

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2
Q

Anti-Basement membrane

A

Goodpasture

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3
Q

Anti-cardiolipin, lupus anticoagulant

A

SLE, antiphospholipid syndrome

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4
Q

Anticentromere

A

Limited scleroderma, CREST

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5
Q

Anti-desmoglein

A

Pemphigus vulgaris

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6
Q

Anti-dsDNA, anti-smith

A

SLE

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7
Q

Anti-glutamate decarboxylase

A

DM1

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8
Q

Anti-hemidesmosome

A

Bullous pemphigoid

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9
Q

Anti-histone

A

Drug induced lupus

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10
Q

Anti-Jo, anti SRP, anti-M2

A

Polymyositis, dermatomyositis

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11
Q

Antimicrosomal, antithryoglobulin

A

Hashimoto thyroiditis

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12
Q

Antimitochondrial

A

1˚ biliary cirrhosis

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13
Q

Antinuclear antibodies

A

SLE, nonspecific

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14
Q

Anti-SCL-70 (anti-DNA Topo-1)

A

Scleroderma (diffuse)

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15
Q

Anti-smooth muscle

A

Autoimmune hepatitis

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16
Q

Anti-SSA, Anti-SSB (Anti-Ro, Anti-La)

A

Sjogren Syndrome

17
Q

Anti-TSH

A

Graves

18
Q

Anti-U1-RNP

A

Mixed CT disease

19
Q

C-ANCA (PR3-ANCA)

A

Granulomatosis w/ polyangiitis (Wegener)

20
Q

IgA antiendomysial, IgA anti-tissue transglutaminase

A

Celiac disease

21
Q

p-ANCA (MPO-ANCA)

A

Microscopic polyangiitis, Churg-Strauss syndrome

22
Q

Rheumatoid factor (anti-Fc region of IgG) - usually IGM

A

RA