Autoantibodies Flashcards
Anti-ACh receptor
Myasthenia gravis
Anti-glomerular basement membrane
goodpasture syndrome
Anti-Beta2 glycoprotein
antiphospholipid syndrome
anti-cardiolipin, lupus anticoagulant
SLE, antiphospholipid syndrome
anticentromere
Limited scleroderma (CREST syndrome)
Anti-desmoglein (anti-desmosome)
pemphigus vulgaris
Anti-glutamic acid decarboxylase, islet cell cytoplasmic antibodies
Type I diabetes mellitus
anti-hemidesmosome
bullous pemphigoid
Anti-synthetase (anti-Jo-1), anti SRP, anti helicase (anti Mi-2)
polymyositis, dermatomyositis
Anti-microsomal, anti-thyroglobulin, anti- thyroid peroxidase,
hashimoto thyroiditis
anti-mitochondrial
primary biliary cirrhosis
anti-parietal cell, anti-intrinsic factor
pernicious anemia
anti-phospholipase A2 receptor
primary membranous nephropathy
anti-Scl-50 (anti-DNA topoisomerase I)
scleroderma (diffuse)
Anti-smooth muscle
autoimmune hepatitis type 1
anti-SSa, anti-SSb (anti-Ro & anti-La)
Sjogren syndrome
Anti-TSH receptor
Graves disease
Anti-presynaptic voltage gated calcium channel
Lambert Eaton myasthenic syndrome
IgA anti-endomysial, IgA anti-tissue transglutaminase
Celiac disease
MPO-ANCA/p-ANCA
microscopic polyangiitis eosinophilic granulomatosis with polyangiitis (churg-strauss syndrome), ulcerative colitis
PR3-ANCA/c-ANCA
Granulomatosis with Polyangiitis (Wegner)
Rheumatoid factor (IgM antibody against IgG Fc region), anti-CCP (cyclic citrullinated peptide)
Rheumatoid Arthritis
ANA (ANA)
Nonspecific screening antibody, often associated with SLE
Anti-dsDNA, Anti Smith (snRNPs, part of spliceosome)
SLE
