Autoantibodies Flashcards
Anti-centromere Ab
Limited Scleroderma (CREST)
Anti-desmoglein (desmosome) Ab
Pemphigus Vulgaris
Type II HS
Anti-dsDNA, Anti-Smith
SLE
Type III HS
ANti-glutamic acid decarboxylase (GAD-65) Ab
Type I DM
Type IV HS
Anti-hemidesmosome
Bulbous Pemphigoid
Type II HS
Anti-histone Ab
Drug-induced SLE (Procainamide, Hydralazine, Isoniazid)
Type III HS
Anti-Jo-1, Anti-SRP, Anti-Mi-2
Polymyositis, dermatomyositis
Antimicrobials, Antithyroglobulin
Hashimoto Thydoiditis
Type IV HS
Antimitochondrial
Primary biliary cirrhosis (cholangitis)
Type IV HS
Antinuclear Ab (ANA)
SLE (nonspecific)
Type III HS
Antiparietal cell
Pernicious Anemia
Type IV HS
Antiphospholipase A2 receptor
Primary membranous nephropathy
Anti-Scl-70 Ab (Anti-DNA topoisomerase I)
Diffuse Scleroderma
Type II HS
ANti-smooth muscle, Anti-LKM (liver, kidney, microsomal), Antinuclear Ab (ANA)
Autoimmune Hepatitis Type I
Anti-SSA (Anti-Ro), Anti-SSB (Anti-La)
Sjogren Syndrome
Type II HS
Anti-TSH receptor
Graves Disease
Type II HS
Anti-U1 RNP (ribonucleoprotein)
Mixed connective tissue disease
Voltage-gated Ca2+ channel Ab
Lambert-Eaton Syndrome
Type II HS
Anti-endomysial IgA, Anti-tissue glutaminase IgA
Celiac Disease
Type IV HS
MPO-ANCA (p-ANCA)
Microscopic Polyangiitis, Eosinophilic Granulomatosis w/ Polyangiitis (Churg-Strauss)
PR3-ANCA (c-ANCA)
Granulomatosis w/ Polyangiitis (Wegener)
Rheumatoid factor (IgM targets Fc of IgG), Anti-CCP
Rheumatoid Arthritis (Anti-CCP more specific) Type IV HS
Anti-ACh receptor Ab
Myasthenia Gravis
Type II HS
Anti-basement membrane Ab
Goodpasture Syndrome
Type II HS
