autoantibodies Flashcards
1
Q
ANA target
A
antinuclear antibodies - bind to contents of cell’s nucleus
2
Q
anti - La disease
A
sjogren syndrome
3
Q
rheumatoid factor target
A
most commonly IgM
specific to IgG Fc region
4
Q
anti - SCL - 70 target
A
anti - DNA topoisomerase I
5
Q
anti - tTG disease
A
celiac disease
6
Q
pANCA disease
A
microscopic polyangitis
churg-strauss syndrome
7
Q
anti - TSH receptor target
A
thyroid receptor
8
Q
anti - Ro target
A
anti - SSA - ribonucleoproteins
9
Q
anti - dsDNA disease
A
SLE
10
Q
anti - actin target
A
actin
11
Q
cANCA target
A
proteins in neutrophil cytoplasm
12
Q
anti - CCP disease
A
rheumatoid arthritis
13
Q
anti - centromere target
A
centromere
14
Q
anti - La target
A
anti - SSB - ribonucleoproteins
15
Q
anti - actin disease
A
celiac disease (# of antibodies correlated w/level of intestinal damage)
