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Auto-antibodies Flashcards

1
Q

Cardiolipin

A

Anti-phospholipid syndrome

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2
Q

Apolipoprotein H / anti-β2 glycoprotein

A

Anti-phospholipid syndrome

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3
Q

Smooth muscle

A

Autoimmune hepatitis

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4
Q

Liver Kidney Microsomal

A

Autoimmune hepatitis

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5
Q

Soluble Liver Antigen

A

Autoimmune hepatitis

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6
Q

Actin

A

Autoimmune hepatitis

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7
Q

Rhesus

A

AIHA

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8
Q

pANCA / MPO (Perinuclear)

A

Churg Strauss

Microscopic polyangiitis

Primary sclerosing cholangitis

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9
Q

cANCA / proteinase-3 (Cytoplasmic)

A

Wegner’s

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10
Q

Platelet (GPIIb/IIIa)

A

ITP

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11
Q

dsDNA (Homogenous)

A

SLE

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12
Q

Ro (Speckled)

A

SLE

Sjogren’s

Congenital Heart Block

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13
Q

La (Speckled)

A

SLE

Sjogren’s

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14
Q

Sm (Speckled)

A

SLE

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15
Q

U1RNP (Speckled)

A

SLE

MCTD

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16
Q

Endomysial (IgA)

A

Coeliac

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17
Q

Tissue Trans Glutaminase (IgA)

A

Coeliac

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18
Q

Gliadin (IgG / IgA)

A

Coeliac

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19
Q

Jo-1 (t-RNA synthetase) (Cytoplasmic speckled)

A

Dermatomyositis

Polymyositis

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20
Q

SCL-70 (Topoisomerase) (Nucleolar)

A

Diffuse Systemic sclerosis

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21
Q

RNA Pol 1,2,3 (Nucleolar)

A

Diffuse Systemic sclerosis

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22
Q

Centromere

A

CREST

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23
Q

Fibrillarin (Nucleolar)

A

Diffuse Systemic sclerosis

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24
Q

GBM (NC α3 collagen IV)

A

Goodpastures

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25
TSH
Graves
26
Tg
Hashimoto’s
27
TPO
Hashimoto’s | Graves (50%)
28
ACh
Myasthenia
29
Voltage gated Ca channels
Lambert-Eaton
30
Parietal cells
Pernicious anaemia / AI gastritis
31
Intrinsic factor
Pernicious anaemia / AI gastritis
32
Mitochondrial (cytoplasmic)
Primary biliary cirrhosis
33
CCP
Rheumatoid arthritis
34
GAD
DM
35
Desmosomes (cadherins)
Pemphigus
36
Hemidesomosomes (collagen XVII)
Pemphigoid
37
Histone
Drug-induced lupus
38
AIHA
Rhesus
39
Anti-phospholipid syndrome
Cardiolipin Apolipoprotein H / anti-β2 glycoprotein
40
Autoimmune hepatitis
Smooth muscle Liver Kidney Microsomal Soluble Liver Antigen Actin
41
Churg Strauss
pANCA / MPO (Perinuclear)
42
Coeliac
Endomysial (IgA) Tissue Trans Glutaminase (IgA) Gliadin (IgG / IgA)
43
Congenital heart block
Ro (Speckled)
44
CREST
Centromere
45
Dermatomyositis
Jo-1 (t-RNA synthetase) (Cytoplasmic speckled)
46
Diffuse Systemic sclerosis
SCL-70 (Topoisomerase) (Nucleolar) RNA Pol 1,2,3 (Nucleolar) Fibrillarin (Nucleolar)
47
DM
GAD
48
Drug-induced lupus
Histone
49
Goodpastures
GBM (NC α3 collagen IV)
50
Graves
TSH TPO (50%)
51
Hashimoto’s
TPO Tg
52
ITP
Platelet (GPIIb/IIIa)
53
Lambert-Eaton
Voltage gated Ca channels
54
MCTD
U1RNP (Speckled)
55
Microscopic polyangitis
pANCA / MPO (Perinuclear)
56
Myasthenia
ACh
57
Pemphigoid
Hemidesomosomes (collagen XVII)
58
Pemphigus
Desmosomes (cadherins)
59
Pernicious anaemia / AI gastritis
Parietal cells | Intrinsic factor
60
Polymyositis
Jo-1 (t-RNA synthetase) (Cytoplasmic speckled)
61
Primary biliary cirrhosis
Mitochondrial (cytoplasmic) Ant-smooth muscle
62
AI hepatitis
Anti-smooth muscle
63
Primary sclerosing cholangitis
pANCA / MPO (Perinuclear)
64
Rheumatoid arthritis
CCP Rheumatoid factor (IgM against the Fc portion of IgG)
65
Sjogren’s
Ro (Speckled) La (Speckled)
66
SLE
dsDNA (Homogenous) Ro (Speckled) La (Speckled) Sm (Speckled) U1RNP (Speckled)
67
Wegner’s
cANCA / proteinase-3 (Cytoplasmic)

Quick Pathology (7 decks)

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