ANA auto-antibodies staining (pattern, antigen, disease) Flashcards
1
Q
Pattern: Homogenous
E.g.?
A
dsDNA
2
Q
Pattern: Speckled
E.g.?
A
Ro
La
Sm
U1RNP
3
Q
Pattern: Nucleolar
E.g.?
A
Topoisomerase (SCL-70)
RNA Polymerase
Fibrillarin
4
Q
Pattern: Cytoplasmic (speckled)
E.g.?
A
Jo-1 (tRNA synthestase)
5
Q
dsDNA
A
Homogenous
SLE
6
Q
Ro
A
Speckled
SLE, Sjogrens
7
Q
La
A
Speckled
SLE, Sjogrens
8
Q
Sm
A
Speckled
SLE
9
Q
U1RNP
A
Speckled
SLE, MCTD
10
Q
Topoisomerase (SCL-70)
A
Nucleolar
Diffuse systemic sclerosis
11
Q
RNA Polymerase
A
Nucleolar
Diffuse systemic sclerosis
12
Q
Fibrillarin
A
Nucleolar
Diffuse systemic sclerosis
13
Q
Jo-1 (tRNA synthestase)
A
Cytoplasmic (speckled)
Dermatiomyositis, Polymyositis
14
Q
Diffuse systemic sclerosis
A
Topoisomerase (SCL-70)
RNA Polymerase
Fibrillarin
(all nucleolar)
15
Q
SLE
A
dsDNA (homogenous) Ro (speckled) La (speckled) Sm (speckled) U1RNP (speckled)
16
Q
MCTD
A
U1RNP (speckled)
17
Q
Sjogrens
A
Ro (speckled)
La (speckled)
18
Q
Dermatiomyositis, Polymyositis
A
Jo-1 (tRNA synthestase)
